At press conference of Health, Labour and Welfare Ministry on March 24, 2017, Dr. Ikuo Tomioka, an assistant professor of Institute for Biomedical sciences in ICCER, announced that his research team successfully generated a transgenic primate model of neurological degeneration diseases, which recapitulates the human disease process including the accumulation of misfolded proteins and neuronal cell loss, resulting in neurologic symptoms. This study was collaborated with National Center of Neurology and Psychiatry. For further details, please see the topics in homepage of National Center of Neurology and Psychiatry (Japanese only) or see an article in homepage of eNeuro which carries an original paper (English only).
National Center of Neurology and Psychiatry: <http://www.ncnp.go.jp/press/release.html?no=341>
eNeuro: <https://doi.org/10.1523/ENEURO.0250-16.2017>


<Information of original paper>
Title: "Transgenic monkey model of the polyglutamine diseases recapitulating progressive neurological symptoms”
Author: Ikuo Tomioka, Hidetoshi Ishibashi, Eiko N. Minakawa, Hideyuki H. Motohashi, Osamu Takayama, Yuko Saito, H. Akiko Popiel, Sandra Puentes, Kensuke Owari, Terumi Nakatani, Naotake Nogami, Kazuhiro Yamamoto, Satoru Noguchi, Takahiro Yonekawa, Yoko Tanaka, Naoko Fujita, Hikaru Suzuki, Hisae Kikuchi, Shu Aizawa, Seiichi Nagano, Daisuke Yamada, Ichizo Nishino, Noritaka Ichinohe, Keiji Wada, Shinichi Kohsaka, Yoshitaka Nagai, Kazuhiko Seki
Magazine which carries an article: eNeuro
DOI: 10.1523/ENEURO.0250-16.2017
URL: https://doi.org/10.1523/ENEURO.0250-16.2017