On December 24th, 2013, the research group of Professor Keiichi Higuchi of the Department of Aging Biology, Institute of Pathogenesis and Disease Prevention announced “New Findings Regarding the Mechanisms of Aging Retardation by the Reduced Form of Coenzyme Q10”.

This research carried out in collaboration with Kaneka Corporation highlights the new mechanisms by which supplementation of reduced form of the coenzyme Q10 (CoQ10H2) slows down the progression of aging and age-related hearing loss in mice. Importantly, this study revealed that the increase in the quantity and activity of mitochondria mediated by the Sirtuin genes (considered to be longevity genes) underlies the aging retardation effects of CoQ10H2.
These research results have been published in the prestigious international journal “Antioxidants and Redox Signaling”.