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E-brochureLegal Medicine

Master's Program Human Sciences, Graduate School of Medicine
Doctor's Program Medical Science Division, Department of Medical Science, Graduate School of Medicine, Science and Technology

Staff List

Professor ASAMURA Hideki
Assistant Professor KOBAYASHI Kanya

Contact

E-mail : houigaku(at)shinshu-u.ac.jp
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Summary of Activity

Personal identity using the DNA typing has progressed rapidly in these last few decades. The problem with which forensic scientists have recently been confronted involves the technical difficulty of analyzing degraded DNA samples. Our main research field is the DNA typing of degraded DNA samples. Also, we are researching forensic pathology and molecular genetics in sudden death.

Research Subject

  • ・ DNA typing of degraded DNA samples
  • ・ Relationship between sudden death of elderly people and amyloidosis
  • ・ Molecular analysis in sudden death cases among patients administered psychotropic drug therapy

Outlook for Research

We have a great societal responsibility for the cause of death investigation. Developments in forensic research will lead to increase of the accuracy of the cause of death investigation.

Major Publications

1. Development of Multiple Assays using 46 SNPs for Comprehensive mtDNA Haplogrouping and Application to Highly Degraded DNA. Nunotani M, Sato N, Kamei S, Shiozaki T, Hayashi T, Asamura H. J Forensic Sci. 61:472-477.2016

2. Analysis of 30 insertion-deletion polymorphisms in the Japanese population using the Investigator DIPplex® kit. Nunotani M, Shiozaki T, Sato N, Kamei S, Takatsu K, Hayashi T, Ota M, Asamura H. Legal Medicine. 17:467-470.2015.

3. Molecular analysis of potassium ion channel genes in sudden death cases among patients administered psychotropic drug therapy: are polymorphisms in LQT genes a potential risk factor?
Kamei S, Sato N, Harayama Y, Nunotani M, Takatsu K, Shiozaki T, Hayashi T, Asamura H. J Hum Genet. 59:95-99,2014.

4. Analysis of Y chromosome haplogroups in Japanese population using short amplicons and its application in forensic analysis. Harayama Y, Kamei S, Sato N, Hayashi T, Shiozaki T, Ota M, Asamura H. Legal Medicine. 16:20-25,2014.

5. Oki T, Hayashi T, Ota M, Asamura H. (2012) Development of multiplex assay with 16 SNPs on X chromosome for degraded samples. Leg Med 14(1): 11-16.

6. Asamura H, Shiozaki T, Sato N, Hayashi T. (2012) Trial investigation of post-mortem non-invasive transnasal endoscopy. Forensic Science Int 220: 184-190.

7. Asamura H, Oki T, Ota M, Fukushima H. (2010) Unusual body posture after death leading to signs of stangulation. Am J Forensic Med Pathol 31: 195-197.

8. Oki T, Asamura T, Hayashi T, Ota M. (2010) Unusual intracranial stab wounds inflicted with mental tent stakes for a case involving a family murder suicide. Forensic Science Int 202: 19-21.

9. Kitayama T, Ogawa Y, Fujii K, Nakahara H, Mizuno N, Sekiguchi K, Yurino N, Yokoi T, Fukuma Y, Yamamoto K, Oki T, Asamura H, Fukushima H. (2010) Evaluation of a new experimental kit for the extraction of DNA from bones and teeth using a non-powder method. Leg Med 12: 84-89.

10. Asamura H, Hayashi T, Oki T, Ota M, Fukushima H. (2009) An Unusual Case of Shaken Baby Syndrome Involving a Popular Baby Chair. Res.Pract.Forens med 52: 217-220.

11. Asamura H, Ito M, Fukushima H. (2009) An Unusual Suicide Case of the Combination of Asphyxia. Am J Forensic Med Pathol 30: 215-217.

12. Asamura H, Fujimori S, Ota M, Oki T, Fukushima H. (2008) Evaluation of miniY-STR multiplex PCR systems for extended 16 Y-STR loci. Int J Leg Med 122: 43-49.

13. Asamura H, Ota M, Fukushima H. (2008) Population data on 10 non-CODIS STR loci in Japanese population using a newly developed multiplex PCR system. J Forensic Leg Med 15: 519-523.

14. Asamura H, Fujimori S, Ota M, Fukushima H. (2007) MiniSTR multiplex systems based on non-CODIS loci for analysis of degraded DNA samples. Forensic Science Int 173: 7-15

15. Asamura H, Sakai H, Kobayashi K, Ota M, Fukushima H. (2006) MiniX-STR multiplex system population study in Japan and application to dengraded DNA analysis. Int J Leg Med 120: 174-181.

16. Asamura H, Sakai H, Ota M, Fukushima H. (2006) Japanese population data for eight X-STR loci using two new quadruplex systems. Int J Leg Med 120: 303-309.

17. Asamura H, Uchida R. Takayanagi K, Ota M, Fukushima H. (2006) Allele frequencies of the six miniSTR loci in a population from Japan. Int J Leg Med 120: 182-184.

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