学術論文・書籍

学術論文・書籍（2015年以降）

2019（R1）年

  • Dai J, Ding X, Miyahara H, Xu Z, Cui X, Igarashi Y, Sawashita J, Mori M, Higuchi K. Suppression of Mouse AApoAII Amyloidosis Progression by ~Daily Supplementation with Oxidative Stress Inhibitors. Oxid Med Cell Longev, (2019) 2019: 1263274. （doi: 10.1155/2019/1263274）
  • 森 政之, 樋口京一。老化研究のためのモデルマウス　―老化促進モデルマウスを軸にして―。日本薬理学雑誌（Folia Pharmacol. Jpn.）（2019）153 (4): 179 -185.

2018（H30）年

  • Huo J, Xu Z, Hosoe K, Kubo H, Miyahara H, Dai J, Mori M, Sawashita J, Higuchi K. Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells. Oxid Med Cell Longev, (2018) 2018: 3181759.
  • Yang M, Liu Y, Dai J, Li L, Ding X, Xu Z, Mori M, Miyahara H, Sawashita J, Higuchi K. Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure. Sci Rep. (2018) 8(1): 5620.
  • Ding X, Liu Y, Yang M, Li L, Miyahara H, Dai J, Xu Z, Matsumoto K, Mori M, Higuchi K, Sawashita J. Amyloidosis-inducing activity of blood cells in mouse AApoAII amyloidosis.
    Exp Anim. (2018) 67(2):105-115. Epub 2017 Oct 30.
  • Miyahara H, Sawashita J, Ishikawa E, Yang M, Ding X, Liu Y, Hachiya N, Kametani F, Yazaki M, Mori M, Higuchi K. Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis. J Proteomics. (2018) 172: 111-121. Epub 2017 Oct 6.
  • 樋口京一；全身性アミロイドーシスの伝播 Dementia Japan （2019） 33 (1): 23-30.
  • 樋口京一。信州大学医学部国際交流推進室International Relations Office, Shinshu University School of Medicine (OICE)の活動紹介とご支援のお願い。松医会報 (2019) 107：65-66.

2017（H29）年

  • Xu Z, Huo J, Ding X, Yang M, Li L, Dai J, Hosoe K, Kubo H, Mori M, Higuchi K, Sawashita J. Coenzyme Q10 improves lipid metabolism and ameliorates obesity by regulating CaMKII-mediated PDE4 inhibition. Sci Rep 7:(2017) 8253, Epub 2017 Aug 15.
  • Akiguchi I, Pallas M, Bubka H, Akiyama H, Ueno M, Han J, Yagi H, Nishikawa T, Chiba Y, Sugiyama H, Takahashi R, Unno K, Higuchi K, Hosokawa M. SAMP8 mice as a neuropathologicalmodel of accelerated brain aging and dementia: Toshio Takeda’s legacy and future directions. Neuropathogy(2017) 37(4): 293-305. Online 2017 Mar 6.
  • Li L*, Sawashita J*, Ding X, Yang M, Xu Z, Miyahara H, Mori M, Higuchi K. Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis. PLoS ONE(2017) 12(2): e0172402, Epub 2017 Feb 22. (*, equal contribution)
  • Yoshinaga T, Yazaki M, Kametani F, Sekijima Y, Iesato Y, Miyahara T, Tsuchiya-Suzuki A, Sano K, Higuchi K, Ikeda SI. Marked biochemical difference in amyloid proportion between intra- and extraocular tissues in a liver-transplanted patient with hereditary ATTR amyloidosis. Amyloid(2017) 13(1):1-7.
  • 樋口京一。動物のアミロイドーシス。『アミロイドーシス – state of art』、安東由喜雄編、医歯薬出版、東京、(2017)pp 237-243
  • Sawashita J, Xu Z, Higuchi K. Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions. “Coenzyme Q in Aging”, Lopez-Lluch G, Navas P eds, Springer, Netherlands, in press.
  • “XVth International Symposium on Amyloidosis”, P. Westermark, G.T. Westermark, & O.B. Suhr eds, Amyloid 24(S1), Informa Healthcare (UK). Published on 22 April.
    1. Yang M, Liu Y, Li L, Miyahara H, Ding X, Dai J, Sawashita J, Mori M, Higuchi K. Apolipoprotein A-II accelerates reactive AA amyloidosis. pp.147-8.
    2. Sawashita J, Li L, Liu Y, Ding X, Yang M, Xu Z, Higuchi K. Caloric restriction prevents the progression of murine AApoAII amyloidosis. pp.171-2.

2016（H28）年

  • Yang M, Liu F, Higuchi K, Sawashita J, Fu X, Zhang L, Zhang L, Fu L, Tong Z, Higuchi K. Serum amyloid A expressed in the breast cancer tissue is associated with poor prognosis. Oncotarget 7(24):35843-52, Epub 2016 Apr 2.
  • Liu Y, Sawashita J, Wang Y, Li L, Miyahara H, Ding X, Yang M, Higuchi K. Distribution of transmissible amyloid proteins in the liver with apolipoprotein A-II amyloidosis. Shinshu Med J 64(4):183-194.
  • Yoshinaga T, Yazaki M, Sekijima Y, Kametani F, Miyashita K, Hachiya N, Tanaka T, Kokudo N, Higuchi K, Ikeda S. The pathological and biochemical identification of possible seed-lesions of transmitted transthyretin amyloidosis after domino liver transplantation. J Pathol: Clin Res 2(2):72-9 (April), Epub 2016 Jan 21.
  • 樋口京一。アミロイド線維の伝播とアミロイドーシスの発症。『臨床検査学教育』、8巻1号、pp.621-7。
  • 樋口京一。アミロイドーシス伝播の動物モデル。『Neuroinfection』、第21巻1号、pp. 80-7。
  • 樋口京一、澤下仁子。全身性アミロイドーシスの疾患感受性と個体間伝播。『医学のあゆみ アミロイドーシスの最新情報』、258卷6号、医歯薬出版、pp. 621-7。
  • "Proceedings: The XIVth International Symposium on Amyloidosis. “Amyloid: Insoluble, but Solvable" ”, B. Kluve-Beckerman, J.J. Liepnieks, & M.D. Benson eds, 309 pages, Indianapolis, (USA). Published on February.
    1. Sawashita J, Zhang B, Kametani F, Naiki H, Higuchi K. The C-terminal sequence of mouse type F apolipoprotein A-II may inhibit AApoAII amyloid fibril formation by blocking the seeding activity of amyloid fibrils. pp.196-9.
    2. Luo H, Sawashita J, Tian G, Liu Y, Li L, Ding Z, Xu Z, Yang M, Miyahara H, Mori M, Qian J, Wang Y, Higuchi K. Deposition of mouse senile AApoAII amyloid fibrils induced unfolded protein responses in the liver, kidney and heart. pp.200-3.

2015（H27）年

  • Yazaki M, Yoshinaga T, Sekijima Y, Nishio S, Kanizawa Y, Kametani F, Miyashita K, Hachiya N, Higuchi K, Ikeda S. The first pure form of Ostertag-type amyloidosis in Japan: a sporadic case of hereditary fibrinogen Aα-chain amyloidosis associated with a novel frameshift variant. Amyloid 22(2):142-4, Epub 2015 May 27.
  • Zhang Y, Hashimoto S, Fujii C, Hida S, Ito K, Matsumura T, Sakaizawa T, Morikawa M, Masuki S, Nose H, Higuchi K, Nakajima K, Taniguchi S. NFκB2 gene as a novel candidate that epigenetically responds to interval walking training. Int J Sports Med Epub 2015 Apr 22.
  • Sawashita J, Zhang B, Hasegawa K, Mori M, Naiki H, Kametani F, Higuchi K. C-terminal sequence of amyloid-resistant type F apolipoprotein A-II inhibits amyloid fibril formation of apolipoprotein A-II in mice. Proc Natl Acad Sci USA 12(8):E836-E845 (Feb 24), Epub 2015 Feb 9.
  • Shoji H, Kiniwa Y, Okuyama R, Yang M, Higuchi K, Mori M. "A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2p) in mice". Exp. Anim. 64(2):171-9 (May 13), Epub 2015 Jan 22.
  • 森 政之。ABCB1A欠損マウスにおける潰瘍性大腸炎。『BIO Clinica』、北隆館、30巻14号、pp. 76-80。
  • 澤下仁子、樋口京一。還元型コエンザイムQ10によるアンチエイジング。『コエンザイムQ10の基礎と応用』、日本コエンザイムQ協会編、丸善プラネット(東京)、pp.170-86。
  • 樋口京一。AApoAII アミロイドーシス。『Clinical Neuroscience』（月刊臨床神経科学）、33巻3号、pp. 337-41。