Research Seeds

PDF AMPK-Activated Endogenous Monosaccharide: Verification of Exercise Effect Enhancement by 1,5-AF

【Supercategory:7. DESCENTE SPORTS SCIENCE Subcategory:7.42 Vol.42

 ABSTRACT

 AMP-activated protein kinase (AMPK) activation is expected to prevent frailty. In this study, we evaluated the effects of AMPK on the behavior of aging-accelerated mice(started in Senescence Accelerated Mouse Prone 8:SAMP8) . The mice were divided into AMPK-activated monosaccharide group and control diet group. After 9 months, the mice were raised freely in the cages and analyzed by the SMART video imaging system using an open field, but there was no significant difference between the two groups( n=12) . The study did not demonstrate efficacy of this monosaccharid.

DECENTE SPORTS SCIENCE Vol.42/The DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
Researcher Kiyoshi Kikuchi*1, Ikuro Maruyama*2, Eiichiro Tanaka*1, Motohiro Morioka*1, Koki Nakanishi*2
University or institution *1 Kurume University School of Medicine, *2 Kagoshima University

Keywords

AMPK, SAMP, preconditioning, aging, frailty