47Outlook for researchDecellularized tissues have substance-specificfunctions, and by binding to cells, they may beable to create complex biological tissues andorgans inside and outside the body.We also believe that we can develop materialswith unprecedented characteristics by makingfull use of technologies in various fields.Outlook for students after graduationThrough research, I want you to learn to think,act, and work as a team.I hope that you will make use of yourexperience in the laboratory and play anactive role in various fields.Outlook for researchC. militaris contains various bioactive substancessuch as cordycepin, which exhibits anti-tumoractivity. Fruiting body of the fungus is expectedfor applicationsin health-enhancing foods,supplements, cosmetics, and more.Outlook for students after graduationWhile many graduates are employed by foodcompanies, others work atcomputer andchemical companies and as public officials, forexample as plant protection officers.Associate ProfessorNEGISHI JunAssociate ProfessorNOGAWA MasahiroDepartment ofApplied BiologyDepartment ofApplied Biologysystem forAfter receiving a doctorate in TokyoMedicaland Dental University,Associate professor Negishi workedas a JSPS post before coming ADEKAas a research worker. His areas ofresearch are biological materials.AssociateNogawaProfessortook his current position afterworking as an assistant professoratthe Nagaoka University ofTechnology. His principal areas ofresearchappliedaremicrobiology.Promotion of neurite outgrowth of decellularized tissues.Fruiting bodies emerged from silkworm pupaeSubculture1st generationSubculture2nd generationSuccessive cultures reduced fruiting body productivity.Cell introduction into a porous material by VPI.Decellularized tissue obtained by removing cells from livingtissue consists of extracellular matrix (ECM) and is known tohave tissue-specific functions. In our laboratory, we createand analyze decellularized tissue from various tissues, clarifythe factors and characteristics, and aim to apply it to tissueregeneration.Vacuum pressure impregnation method (VPI)used in metal processing is a technology that enables theefficient introduction of solutions into materials. By applyingVPI to biomaterial research, we aim to develop porousmaterials that contain cells and composite materials withnew properties.Chinese caterpillar fungi have been prized as an ingredientin traditional Chinese medicine. Cordyceps militaris isdistributed worldwide and produces orange fruiting bodiesfrom the pupa of lepidopterous insects. Artificial cultivationmethod forthe fungus have been developed, butcontinuous culture frequently results in the degeneration ofthe fungus. This makes large-scale cultivation of the fungusdifficult. My laboratory is trying to develop a stablecultivationreduceddeterioration of the fruiting bodies.Fruiting bodies produced on solid mediumSubculture3rd generationC. militaris withBiomaterials that take advantage of the characteristics of biological tissuesArtificial cultivation system for chinesecaterpillar fungus (Cordyceps militaris)
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