Plastic and Reconstructive SurgeryChief：Prof. ShunsukeYuzurihaLaboratory MedicineDiscovering disease mechanisms that lead to developing therapies for untreatable diseases.Communicating with researchers around the world through international meetings andstudying abroad.・Clinical research of cleft lip and palate, vascular anomaly・Research of facial anthropometry in Japanese・Research for new wound healing by transplanting isolated mitochondria(Mt), analyzing mechanism of regeneration of wounded newts ・Basic and clinical research for severe nail deformity, lip reconstruction and regenerative treatment・Research for new blood flow monitoring using laser speckle flowgraphyKnowing the standard of Japanese each facial part can give an ideal faceto every patient with various facial deformities. It is impossible to reconstructthe loss oflip and fingers/toes completely now. We are studying fromvarious views in order to realize the ideal treatment.S k ills as a surgeon will be trained by experiencing many operation casesof the wide fields at the Shinshu university and affiliated hospitals. After that,working at university as a staff or at affiliated hospitals, or starting practice. • Clinicopathological analysis of tumors focusing on cancer stem cells••Pathogenetic analysis of IgG4-related diseaseImmunohistochemical and genetic investigation ofassociated neoplasms• Development of AI-based pathologicalengineering departmentsAPs and CPs can actively contribute in a variety of workplaces including university and city hospitals, and basic research institutes that take advantage ofbasic and clinical experts. You can select a workplace that best fits your lifestyle.(a)(d)【Laser Speckle Flowgraphy】【Regeneration after forelimb amputation in newt】(b)200nm (c)Western blotting of isolated Mt (c)【Wound Healing Research by Mitochondria】(a)Mt of normal human fibroblasts(b)Electron micrograph of isolated Mt(d)Wound Healing Assay Plastic and reconstructive surgery is the study which searches forthe way by which restores functionally and aesthetically the loss oftissue which has caused by congenital anomalies,injuries andtumor removals. In all medical departments, only our departmentcreates the shape by surgery for treatment. A study and educationare being perfomed, which are directly conjugated to clinicaltreatment by improving visual appearance, a decline of the functionand the quality of life.Research subjectOutlook for researchOutlook for students after graduationIn our laboratory, anatomical pathologists (AP) and clinical pathologists (CP) work with many clinical departments.APs are responsible for pathological diagnoses, which are essential for the clinical diagnoses and treatments that follow. We use up-to-date technology, such as genetic tests, to always provide precise and useful diagnoses. To maintain our level of precision, we haveregular meetings with the clinical departments. The AP’s role is becoming increasingly important in medical fields.CPs are also critical partners in providing suitable clinical tests, maintaining precision control of the tests, and giving informative adviceto clinicians.For example, CPs in the infection control section try to keep up the quality of the medical service by communicating closelyto relevant clinicians.The professional and technical expertise of the APs and CPs in our laboratory, paired with our advanced technology platforms, allow usto provide valuable information to clinicians. Furthermore, we actively conduct research in pathological, genetic, and laboratory fields,among others.Medical doctors as well as technicians are involved in this research.Research subjectOutlook for researchOutlook for students after graduationinflammatory bowel disease–image analysis in collaboration with 31Look for future strategies for heal and regeneration to support the quality of lifeShare the future that anatomical & clinical pathologists cultivate!信州大学医学部医学科発行年月：２０２４年７月 発行：信州大学医学部
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