（Chief: Prof. Mitsuhisa Komatsu）19Artificial pancreas・ Establishment of effective therapeutic approaches to refractory rheumatic and colla-・ Elucidation of pathogenic mechanisms in refractory rheumatic and collagen-vascular dis-・ Genetic diagnosis and investigation of genotype-phenotype correlation of Japanese pa-・ Elucidation of pathogenic mechanisms in neurological involvements related to systemic ・ Multicenter studies based on various clinical questions associated with daily practice for establishing useful diagnostic and therapeutic strategies in systemic lupus erythematosus and adult onset Still’s disease.Outlook for researchSummary of ActivityThe medical care required in the world is changing from “to cure diseases” to “to make people not get illness”. The Diabetes and life style related disease which continue to be spread all over the world can become trigger to many serious dis-eases. We encourage basic and clinical research in order to contribute to realize the extension of healthy life span. And we are also conducting endocrinological reserch actively connecting to life style related disease.Research subjectResearch subjectChief: Associate Prof. Yasuhiro Shimojima））Outlook for students after graduationOutlook for students after graduationgen-vascular diseases.eases.tients with familial Mediterranean fever.vasculitis.The immune system has protected our systemic organs from invasion by several harmful agents and pathogens. However, it can react in attacking ourselves, resulting in the occur-rence of rheumatic disease or collagen-vascular disease. Meanwhile, some patients are still refractory to the treatments. We believe that our investigation of elucidating immune-patho-genesis can develop the effective therapeutic strategy, allowing patients to be in complete remission.Technical skills and knowledges in our lab is useful for developing our career in which we work on the medical care and education as the rheumatologist. Besides, we can subse-quently study more advanced knowledge associated with immunology and rheumatology in the foreign facility for the purpose of developing our research.・Investigation into mechanism of secretion of insulin hormone.・Relations between thyroid hormone and life style related disease.・Investigation of trend of blood glucose level using artificial pancreas.・ Proposals for a new exercise therapy in type 2 diabetes. interval walking training pro-grams. (collaboratiion with Departiment of Sports medical Sciences )Outlook for researchTo research pathology of diabetes, endocrinology and metabolism can lead to establishment of cause-based rather than symptomatic treatment, and this will open the gate of a hopeful future where people will be all healthy and live long. To study basic and clinical research will enable you to acquire objectivity which is most im-portant quality for a medical worker. This area will be more required for the times, and you can play an active role in the world. For the purpose of contributing to medical care, we always develop our technical skills and achieve new approaches in the research.Group photo of medical staff of our department.Research landscape in the laboratory (graduate students)Rheumatology, Clinical immunology Rheumatology, Clinical immunology （（Chief: Associate Prof. Yasuhiro ShimojimaMedicine IIIMedicine IVChallenge to elucidate the mechanisms of autoimmune disorders. To acquire the advanced medical technology and provide the advanced medical care!Open up a bright future towards the extension of healthy life span(Diabetes, Endocrinology and Metabolism)
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