・ Viral hepatitis elimination project in Nagano prefecture. ・Clinical research on anti-viral medicine such as nucleic acid analog therapy and interferon therapy in hepatitis B. ・Clinical research on hepatitis C in Nagano prefecture. ・Disease susceptibility genes and epigenetic interaction in autoimmune liver disease. ・Discovery of novel biomarkers for nonalcoholic fatty liver disease. ・You can spend clinical and research life as a world-class liver physician.15Research subjectResearch subjectChief: Prof. Takeji Umemura））Outlook for research・ Our research goal is to solve important clinical questions using epidemiological and molecular biological approaches. ・We help patients with chronic liver disease worldwide by actively disseminating our research.Outlook for students after graduationOutlook for researchOutlook for students after graduation・Colitis associated with immune checkpoint inhibitor・Barrett’s esophagus/Barrett’s cancer・Helicobacter pylori infection (gastric cancer after eradication)・Near Infrared photoimmunotherapy (NIR-PIT)・Endoscopic surgery for esophageal achalasiaYour articles may change medical care practice around the world. You will gain great knowl-edge through study that will enrich you as a clinician. Good researchers are good clinicians, and good clinicians become good researchers.Most students become general internists with a specialty in gastroenterology and work as hospital doctors, practitioners, university faculty members, and more. You can become the doctor you want to be.Members of our liver teamHepatic examination and treatmentWe need to think critically during endoscopic examinations.New research themes sometimes appear in such situations.Nodular gastritis as a result ofH. pylori infection is a strong risk factor for gastric cancerResearch and discoveryEndoscopic submucosal dissection technique for resection of early cancer in digestive tractStomach and IntestinesStomach and IntestinesSummary of ActivityWe diagnose and treat patients with viral hepatitis, autoimmune liver disease, nonalcoholic fatty liver disease, and other acute or chronic liver diseases. Per-cutaneous liver biopsy, non-invasive serum biomarkers, and Fibroscan® test are used for the diagnosis and evaluation of clinical stages and liver fibrosis stages. For the treatment of liver cancer, we perform radiofrequency ablation therapy, percutaneous ethanol injection therapy, microwave ablation therapy, hepatic artery chemoembolization therapy, and the administration of molecular targeted medicines and immune checkpoint inhibitors.Summary of ActivityWe seek out problems that need solving in routine endoscopic examinations and in/out-patient services. There are still many unsolved subjects, even in common diseases. Your intention to give better treatment to the patient in front of you makes you ask good questions. If you cannot find the answer in the literature, it becomes a suitable subject for research. You can study about it and make con-ference presentations and articles with the help of many colleagues and faculties at our university. You can publish your findings to the world.（（Chief: Prof. Takeji Umemura(Chief: Tadanobu Nagaya)(Chief: Tadanobu Nagaya)Response to clinical questionsNeoplasms, inflammatory bowel diseases, infections, and moreMedicine IILiver TeamLiver TeamMedicine II
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