MaterialsChemistryMaterialsChemistryMaterialsChemistryMaterialsChemistryAbiologicalcellisanextremelysophisticatedmicrochemicalsystem.Thisfacthasledscientiststoconstructacell-likemicrochemicalsystembyhumanhands.Forthesystem,artificialplasmamembranesareessentialastheyseparatetheinnerworldfromtheoutsideandbecometheinterfacebetweenthetwoworlds.Ourresearchgroupstudieslipidmembranevesiclesthathavethesizecomparabletobiologicalcells(giantliposomes)assuchartificialcellmembranes.Sakai’sresearchaimstodevelopthemethodologiesforfabricationofthecolloidalmaterials(e.g.,metalnanoparticles,porousmaterials,emulsions,bubblesandfoam)andorganizationcolloidalmaterialsintomulti-dimensional(1D,2Dand3D)structuresinsolutionsand/oratinterfacesinanefficientmannerwithrespecttocost,energyandenvironment.Inparticular,amphiphiliccharacters(dualnatures)ofmoleculesorpolymersareessentialelementsfordesigningthemethodologies.Colloidalmaterialsandtheirorganizationonsubstratearestronglyrequiredforrecentdevicefabricationbecauseofthedeviceminiaturization.Furthermore,theimprovementofdeviceperformanceisrequiredfortheconvenienceofourdailylife.TheSakai’sresearchgroupattemptstodevelop“high-puritycolloidalmaterials”becausetheyareexpectedtoexhibithigherperformance.suchaspapermaking,Technologicalprocessespotterymakingandthefabricationofsoaps,cosmeticsandmedicinesinvolvemanipulationofcolloidalsystems.Colloidandinterfacescienceprovidesvariousopportunitiesintheindustriessuchascatalyst,electronics,toiletryandmedicalfields.Theconstructionofasophisticatedartificialcellwillbeonetechnologicalachievements.Althoughthereclearlyisalongwayahead,manyresearchgroupsaroundtheworldhavebeenworkingontheproblem.ifestablished,willbeusedinmanybio-relatedfields,suchasmedicineandagriculture.Anexampleofpossibleapplicationsisadrugdeliverysystemmoreefficientandcompatibletohumanbodies.ofthemajorscientificManygraduatesfoundtheircareersinvariouschemistry-relatedfieldsincompanies.Throughthesisworks,studentsinourgroupareexpectedtoimprovetheskillsnecessaryasanengineer;carefulobservation,logicalthinkingandgoodresearchplanning.andThetechnology,Preparation and characterization of colloidal materials such as metal nanoparticles, porous materials, emulsions, bubbles and foam.Optical micrograph of oil-in-water (O/W) emulsion..Emulsions are used in various fields such as cosmetic, food and medical field.Working with giant vesicles. Giant vesicles are as large as biological cells and can be directly observed on an optical microscope.Micromanipulation of a giant vesicle. Various substances may be introduced into the vesicle by microinjection through a hollow needle.O/WYukihisaOkumuraProfessorChemistry of artificial lipid membrane vesicles (liposomes)Bio-mimetic microchemicalsystems.Toshio SakaiProfessorGenesis Research Institute, Inc., The State University of New York, Tokyo University of Science and ShinshuUniversity. Colloid and Interface Science.In the FutureAfter GraduationIn the FutureAfter GraduationArtificial Membrane for Cell-Like MicrochemicalSystemsColloid and Interface Science~Mysterious World Generated from Particles and Interface~
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