39Look for future strategies for heal and regeneration to support the quality of lifeSummary of ActivityPlastic and reconstructive surgery is the study which searches for the way by which restores functionally and aesthetically the loss of tissue which has caused by congenital anomalies, injuries and tumor removals. In all medical departments, only our department creates the shape by surgery for treatment. A study and education are being perfomed, which are directly conjugated to clinical treatment by improving visual appearance, a decline of the function and the quality of life.・Clinical research of cleft lip and palate, vascular anomaly・Research of facial anthropometry in Japanese・Research for new wound healing by transplanting isolated mitochondria, analyzing mech-anism of regeneration of wounded newts・Basic and clinical research for severe nail deformity, lip reconstruction and regenerative treatment・Research for new blood flow monitoring using laser speckle flowgraphyKnowing the standard of Japanese each facial part can give an ideal face to every patient with various facial deformities. It is impossible to reconstruct the loss of lip and fingers/toes completely now. We are studying from various views in order to realize the ideal treatment.Skills as a surgeon will be trained by experiencing many operation cases of the wide fields at the Shinshu university and affiliated hospitals. After that, working at university as a staff or at affiliated hospitals, or starting practice. Research subjectOutlook for researchOutlook for students after graduationPlastic and Reconstructive Surgery（Chief: Prof. ShunsukeYuzuriha）【Regeneration of amputated Newt’s forelimb】【Wound Healing Research using Mitochondria （Mt）】⒜⒝⒞⒟⒠⒜⒝⒞200nm⒠⒟Cultured normal human dermal broblastsImmunohistochemistry of MtElectron micrograph of isolated MtWestern blotting of isolated Mt Wound Healing AssayTomm40COX IVCalnexinHistone H37 dpa37 dpa56 dpa70 dpapellet②（Mt）sup③pellet①sup②sup①【Laser Speckle Flowgraphy】7dpa37dpa70dpa240dpaShare the future that anatomical & clinical pathologists cultivate!Summary of ActivityIn our laboratory, anatomical pathologists (AP) and clinical pathologists (CP) work with many clinical departments.APs are responsible for pathological diagnoses, which are essential for the clinical diagnoses and treatments that follow. We use up-to-date technology, such as genetic tests, to always provide precise and useful diagnoses. To maintain our level of precision, we have regular meet-ings with the clinical departments. The AP’s role is becoming increasingly important in medical fields.CPs are also critical partners in providing suitable clinical tests, maintaining precision control of the tests, and giving informative advice to clini-cians. For example, CPs in the infection control section try to keep up the quality of the medical service by communicating closely to relevant clinicians. The professional and technical expertise of the APs and CPs in our laboratory, paired with our advanced technology platforms, allow us to pro-vide valuable information to clinicians. Furthermore, we actively conduct research in pathological, genetic, and laboratory fields, among others. Medical doctors as well as technicians are involved in this research. ・Clarifying the mechanism of the development of interstitial pneumonia: We are investigating type II pneumocyte cultures to unravel the cause of idiopathic interstitial pneumonia.・Conducting molecular studies of alimentary mucin and digestive tract stem cells・Developing and applying a droplet, high-speed PCR test: We are developing a high-speed PCR device, in cooperation with Seiko Epson, and applying the technology to quickly detect infection, diagnose malignancies, and study the effectiveness of prospective anti-cancer drugs.・Analyzing IgG4-related diseases: We work with with clinical departments to conduct clinicopathological analysis of IgG4-related diseases.・Studying the effectiveness of the left-shifted leukocyte fraction for analysis of bacterial infectionDiscovering disease mechanisms that lead to developing therapies for untreatable diseases.Communicating with researchers around the world through international meetings and studying abroad.APs and CPs can actively contribute in a variety of workplaces including university and city hospi-tals, and basic research institutes that take advantage of basic and clinical experts. You can select a workplace that best fits your lifestyle. Research subjectOutlook for researchOutlook for students after graduationLaboratory Medicine
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