信大医学部研究紹介2021(英語版)_プレス品質
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9Immunological and pathological research on chronic inammationSummary of ActivityA chronic inflammation was finding out in recent years to be resulted in cancer, lifestyle-related diseases, a neurodegeneration diseases, autoimmune diseases etc. Using knockout mice, we are exploring the pathogenesis of tumors and au-toinflammatory diseases and onset factors.・Relationship between colon cancer onset and intestinal bacteria.・Immunological analysis of autoinflammatory diseases. ・Relationship between the function of mucosal sugar chain and infectious disease in developing gastric cancer.Causes of illness are inherited and acquired. Analysis using genetically modified mice has revealed that genetic abnormality is not directly causing carcinogenesis but causes inflammation. Further research will be aimed at leading to the development of new treatments and preventive methods.Researcher.In case of medical doctors, most of the postgraduate students have been back to their own fields.Research subjectOutlook for researchOutlook for students after graduationPathobiology(Chief: Prof. Jun Nakayama)Stomach cancer in N-acetylglucosaminyl transferase-decient miceColon cancer in arylhydrocarbon receptor-decient miceResearch of EtiopathogenesisSummary of ActivityPathology, an unfamiliar research field, clarifies the disease process to death. Pathologists observe the tissue specimens sampled from the lesion of patients, give the diagnosis and further make final diagnosis after autopsy examination. They contribute to the advanced medicine through conferences with clinicians. Pathology, research of etiopathogenesis of diseases, makes the bases of pathologic diagnosis. In our department, we can devote in advanced biomedical research with the pride of physician engaged in patient care.・Collagen disease, vasculitis, glomerulonephritis: Contribution of innate immunity activated by various microorganisms・Epstein-Barr virus-related diseases: Diseases caused by ubiquitous virus in human beings in specific conditions・Prevention and treatment of intractable diseases caused via immune mechanisms・Lower frequency of complications caused with immune suppression in patients receiving advanced medical care・Biomedical research positions in pathology department in medical school・Beneficial experiences in the research of human diseases・Diagnostic pathologists in pathology department in center hospitalsResearch subjectOutlook for researchOutlook for students after graduationPathology(Chief: Prof. Hiroyuki Kanno)Training in diagnostic pathologyMan-to-man training with senior staffObservation of cultured cellsunder inverted microscopeBroad research approachnot restricted in morphology

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