写真サイズ高さ4.35cm×幅3.6cm配置位置横15.3cm、縦2.85cmOutlook for research Makingeffectiveuseofmicroorganismresources:DiscoveringandapplyingthepotentialcapabilitiesofBacillussubtilisOutlook for research Toinvestigatethecharacteristicsofthebiologicalmaterial,todevelopanewmedicaldeviceNative porcine artery: occlusionDecellularized porcine artery: patent53応用生物科学科Department of Applied Biology応用生物科学科Department of Applied BiologyOutlookforstudentsaftergraduationOutlookforstudentsaftergraduationInordertodiscoverthenovelfunctionsandnetworksofthe4,100genesthatmakeuptheBacillussubtilisgenome,mylabiscooperatingwithdomesticandinternationalresearchlabstocarryoutmoredetailedresearch.WebelievethatB.subtilisisanimportantmicroorganismresource,andweareworkingtodevelopadeeperunderstandingofitspotentialsothatwecanutilizeit.Inthefuture,mygoalistoestablishararemetalrecoverysystemusingB.subtilisstrainswithalteredcellwallpolymers,tomakeeffectiveuseofthegeneticresourcesofitsclosestrelatives,andtoapplyassociatedtechnologytothedevelopmentofantibacterialagentsforpathogenicbacteria.Graduatesaretypicallyemployedbyfoodandpharmaceuticalcompanies.Somechoosetocontinuetheirresearchatdomesticandoverseasresearchorganizations.AssociateProfessorHirokiYamamotoAssociateProfessorYamamototookhiscurrentpositionin2007afterservingintheFacultyofTextileScienceandTechnologyatShinshuUniversityasanassistantprofessor.Hisareasofresearchincludemicrobiologytoexaminethepropertiesofmoleculesfunctioninginthecellsofmicroorganismsandappliedmicrobiologytomakeuseofthelatentcapabilitiesofmicrobes.A student uses a fluorescence microscope to assess the effect on the cell when cell wall polymers are modified.Astudentsearchesforbacterialsubstancesthatwillactivatetheimmunesystemofanimalcells.Wealsomakeobservationsusinganelectronmicroscopesowedonotmissslightchanges.Decellularizedtissuesarepreparedfrombiologicaltissues,andareclinicallyusedinEuropeandU.S.Thedecellularizedmaterialsshowbiocompatibilitiesatimplantedsites.Itispossibletotransplantanimaltissuestohumansbydecellularizationtreatments.Theobjectofourresearchisanapplicationandaninvestigationofthesedecellularizedtissuepropertiesforuseinmedicaldevices.Thevacuumpressureimpregnationtechniqueisabletoeasilyrehydratematerials.Ourresearchaimstofabricateanewmedicalmaterialusingthistechnique.Biologicalmaterialssuchasadecellularizedmaterialareabletomimiccomplexstructuresofanimaltissuesandcanbeusedasaremodelingmaterialbypatients’owncells.Itwouldbepossibletofabricatetissuesandorganinvitrobycombiningthesematerialsandstemcells.Usingotherfiledtechniquesmayleadanovelmedicaldevicefabrication.Studentslearntothinkbythemselvesandtakeinitiativeinthisresearchlab,andthispreparesthemtoworkbywellingroupsorbythemselves.Theyareequippedtopursuecareersacrossavarietyofscientificfields.AssistantProfessorJunNegishiAfterreceivingadoctorateinTokyoMedicalandDentalUniversity,AssistantProfessorNegisihworkedasaJSPSpostdoctoratSapporoMedicalUniversitybeforecomingADEKAasaresearchworker.Hisareasofresearcharebiologicalmaterials.(Left)Anativeporcinearteryafter3daysinratcarotidtransplantation.(Right)Adecellularizzedporcinearteryafter2weeksinratcarotidtransplantation(A)Afreeze‐driedaortaafter10minimmersionintoPEG.(B)Afreeze‐driedaortaafterPEGhydrationbyvacuumpressureimpregnation(VPI).TheVPItreatedaortashowedhomogeneousrehydration.
元のページ ../index.html#54