Outlook for research Utilizing Agrobacterium tumefaciens, which carries out genetic engineering on its ownWild type VirE2Modified VirE2NON‐transformantTransformant52応用生物科学科Department of Applied Biology応用生物科学科OutlookforstudentsaftergraduationIamcarryingoutresearchonhowtouseA.tumefaciens,whichhastheabilitytoinsertitsownDNAintothechromosomesofplants,todevelopDNAinsertionmethodsfornumerouscrops;researchtoinfectplantswithA.tumefacienstocreateusefulsubstances;andresearchtoalterA.tumefaciensthroughgeneticengineeringtogivethebacteriumnewcapabilities.Inadditiontocreatingplantsthatdonotneedpesticides,wecancreaterawmaterialsforindustryandpharmaceuticals.Throughtheuseofgeneticallymodifiedplants,thesesubstanceswillbecreatedusingonlysolarenergyandCO2.Whilemanygraduatesareemployedbyfoodcompanies,othersworkatcomputerandchemicalcompaniesandaspublicofficials,forexampleasplantprotectionofficers.AssociateProfessorMasahiroNogawaAssociateProfessorNogawatookhiscurrentpositionafterworkingasanassistantprofessorattheNagaokaUniversityofTechnologyandasanassistantprofessorintheFacultyofTextileScienceandTechnologyatShinshuUniversity.Hisprincipalareasofresearcharegeneticengineeringandappliedmicrobiologyfocusingonplantsandmicroorganisms.VirE2proteintransfersforeignDNAintoplantnucleus.ModifiedVirE2proteinlocalizedinplastid(chloroplast).Blue:nucleus,Green:modifiedVirE2.Transformedmulberryproducedmorecytokininfromiptgenewhichintegratedintoplantgenomebyinplantamethod.Transformantdidnotshowapicaldominance.Outlook for research Movingfromunderstandingoffunctionalbiomoleculestotheirapplication,utilizingunusedproteinresources,anddevelopingproductiontechnologiesTryingtocreatethefunctionallyimprovedproteins(e.g.higherenzymaticactivity),basedonthegeneticandproteinengineeringtechnologies.Weexploreandexaminetheusefulbiomoleculeswithvarioustechniques;astudentisisolatingthetargetproteinbyusingcolumnchromatography.応用生物科学科Department of Applied BiologyOutlookforstudentsaftergraduationIamcarryingoutresearchonproteins,aprincipletypeoffunctionalbiomolecule.Mylabusesmolecularbiologyandgeneticengineeringtechnologytoidentifyandimproveusefulproteinssuchasenzymesandtodevelopprotein‐manufacturingtechnologies.Theidentificationofnewenzymesandtheirimprovementthroughgeneticengineeringareexpectedtocontributetomanydomains,includingfood,medicine,andchemicalsynthesis.Wearealsoattemptingtodeveloptechnologyformakingtheproductionofusefulproteinspossiblethroughalterationofribosomesandrelatedfactorsatthemolecularlevel.Manygraduatesareemployedasresearchersinavarietyoffields,includingbyfoodandpharmaceuticalcompaniesandchemicalmanufacturersthathandlevariousmaterials.AssociateProfessorTakaomiNomuraAssociateProfessorNomuratookhiscurrentpositionin2017afterworkingattheLionCorporationResearchCenterandasaresearchassociateandassistantprofessorintheFacultyofTextileScienceandTechnologyatShinshuUniversity.Hisprincipalareaofresearchistheanalysisoffunctionalbiomoleculesusingmolecularbiologyandgeneticengineeringtechnology.
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