繊維学部研究紹介_2020_英語版
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Outlook for research Using insects’ high‐performance sensors to develop methods for exterminationSilkworm eggs. Non‐diapause eggs hatched 9–10 d after oviposition (left), but diapause eggs never hatched 60 d after oviposition, and normal embryogenesis was arrested (right).50応用生物科学科Department of Applied BiologyDepartment of Applied BiologyDepartment of Applied BiologyIamcarryingoutresearchonthesensorscarriedbyinsectstomonitorthearrivaloftheseasonsviasensorproteinsthatrespondtotemperatureanddaylength.Myfindingscanbeappliedtotheexterminationofpestsandinvasivespeciesthroughsuchtechniquesascausingeggstohatchinwinterandmakingadultinsectswithoutwingsgrowthem.Thisapproachisgarneringattentionasapestexterminationmethodthatdoesnotharmnatureorhumans.Theabilitytocontrolthedormantstageofinsectsisusefulnotonlyforexterminatingpests,butalsoforprotectingecosystems.Further,Ibelievethatexplainingtheecologyofinsectscancontributesolutionsforglobalenvironmental,food‐related,andmedicalproblems.Graduatescanfindemploymentatfoodandpharmaceuticalcompanies,environmentalcompaniesworkingwithnature,companiesengagedingeneticanalysis,andeventrade‐relatedinspectioncompanies.OutlookforstudentsaftergraduationAssociateProfessorKunihiroShiomiAssociateProfessorShiomitookhiscurrentpositionin2007afterservingintheFacultyofTextileScienceandTechnologyatShinshuUniversityasanassistantprofessor.Hisareasofresearchincludeenvironmentalmolecularentomologyandappliedentomologywithafocusonthedormancy,metamorphosis,andseasonalmorphologyofinsects.Astudentobservesculturedcellsintowhichinsectsensorgeneshavebeeninserted.UsefulgenesareclonedfrominsectsoftheorderLepidoptera.サイズW7.5cm×H4.35cm配置位置横11cm、縦7.8cmOutlook for research Designing and developing useful proteins by studying the structure and function of proteins応用生物科学科Department of Applied BiologyOutlookforstudentsaftergraduationDepartment of Applied BiologyWearecarryingoutresearchtogainadeeperunderstandingofthestructureandfunctionofproteinsandtodesign,develop,andapplyusefulartificialandengineeredproteins.Inthefieldsofproteindesignandengineering,ourlabusescuttingedgetechnologytosee,analyze,create,andapplyusefulproteins.Ourgoalistoapplyproteinsinvariousfields,forexampleinbiotechnologyandpharmaceuticaldevelopment,inordertodevelopeco‐friendlyhighlyfunctionalnanomaterials,greenchemistrycatalysts,high‐sensitivitybiosensors,andeffectivevaccines.Intheseways,wehopetocontributetheachievementofasustainablesociety.Graduatesareemployedinnumerousfields,includingatfood,pharmaceutical,optics,chemical,andbiochemicalcompanies.AssociateProfessorRyoichiAraiAssociateProfessorAraijoinedShinshuUniversityin2007afterworkingasaresearcheratRIKENandPrincetonUniversityintheU.S.Hisareasofresearcharestructuralbiologytoanalyzethethree‐dimensionalstructureandfunctionofproteins,andproteinengineeringtodevelopusefulproteinsthroughtheirmodificationanddesign.Anexperimentintheresearchlab(upperleft),productionofusefulproteinswithmicroorganisms(upperright),proteincrystalswhichshinelikeapreciousstone(lowerleft),andanX‐raydiffractionexperimentatasynchrotronradiationfacility(lowerright)Self‐assemblingnanoarchitecturesarecreatedfromaproteinnano‐buildingblockbyfusingadimericdenovoproteinWA20andatrimericfoldondomainfromT4phage.(Kobayashi,N.etal.,J.Am.Chem.Soc.,137,11285‐11293,2015)

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