信大医学部医学科研究紹介2020(英語版)
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27To offer the most appropriate and advanced care for the patientsCardiovascular SurgeryCardiovascular Surgery((Chief:Prof. Tatsuichiro SetoChief:Prof. Tatsuichiro Seto))SurgerySummary of ActivityWe are conducting surgical treatment for cardiovascular diseases, peripheral vascular diseases including venous and lymphatic vessels, from heart disease to peripheral organs in the body as a whole. Particularly in multidisciplinary therapy for patients with severe systemic complications, elderly patients, patients with complex lesions, taking advantage of the university hospital, we offer medical treatment aiming for safer and more reliable surgery considering the patient’s long-term prognosis.・Research and development of cardiac regenerative therapy using iPS cell.・Research and development of surgery for thoracoabdominal aneurysm.・Research and development of novel site-selective ischemic disease therapeutic using recombinant bifidobacteria・Research and development of cardiac allograft rejection In medicine, it is said that today’s contraindications are tomorrow’s indications.Things that are forbidden today because something cannot be overcome may be permitted tomorrow thanks to just one breakthrough.We run practical training programs with specific goals that include understanding all charged cases and diseases, learning basic surgical procedures, and improving presentation tech-niques.Research subjectOutlook for researchOutlook for students after graduationState of cardiac surgeryCardiac regenerative therapy using iPS cell.“Modified from Shiba, et al. Nature 2016;  538: 388-391.”novel site-selective ischemic disease therapeutic using recombinant bidobac-teriaWe Aim to be Number One!General Thoracic SurgeryGeneral Thoracic Surgery((Professor Kimihiro Shimizu, MD, PhDProfessor Kimihiro Shimizu, MD, PhD))SurgerySummary of ActivityThe brand-new Division of General Thoracic Surgery, Department of Surgery was born in August 2019 with an appointment of Professor Kimihiro Shimizu. We treat a variety of thoracic diseases including thoracic malignancies such as a lung cancer, and thymic epithelial tumors (thymoma, thymic cancer); benign diseases such as pneumothorax, and inflammatory lung diseases, and chest trauma. We specifically provide patients with following surgeries aggressively, a “surgery without pain” utilizing a thoracoscope to reduse physical invasiveness and postoperative pain, and a “surgery without shortness of breath” or a seg-mentectomy to preserve nomal lung volume utilizing three-dimensional computed tomographic (3D-CT) images in patients with small, early-stage lung cancer. ・To investgate a segmental anatomy of the lungs utilizing 3D-CT images to develop novel surgical strategies to preserve lung volume in patients (Figure)・To integrate lung regeneration technologies and lung preserving surgical strategies to es-tablish safer and oncologically more effective treatment for lung cancer・To investgate a clinical and molecular pathology of lung cancerOur research target is mainly a lung cancer, which has the highest mortality rate among all malignancies. All our efforts in lung cancer research will lead to interests of individual pa-tients and development of future thoracic surgery.After graduation, you should become an international “academic surgeon” who can treat pa-tients with an evidence-based and personalized approaches and publish your achievements based on basic and/or clinical investigations to pursue various questions/interests in clinical practice. Let us aim to become a superb thoracic surgeon who have excellent clinical know ledges with genune skills, and develop together a “number one” thoracic surgery group in Japan and in the world.Research for the futureOur research projectsVision after graduation3D-CT imagesLobectomySegmentectomyRight upperlobectomyUpperUpperlobelobeMiddleMiddlelobelobeLowerLowerlobelobeRight upper lobeS1 segmentectomy

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