信大医学部医学科研究紹介2019（英語版）

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28Development of New Treatments for Diseases in Summary of ActivityBasic research・ Over 10 members have joined the Shinshu Univ. Institute for Bio-medical Science for biomaterial research with a focus on carbon nanotubes・ Departmental collaborations at Shinshu Univ. School of Medicine to conduct research on bone, cartilage, muscle and nerve ・ Collaborative research with the Institute of Fiber Engineering on spinal biomechanics・ Fiber biology, drug design for osteosarcoma, bone biology Clinical research・ Cohort study to investigate musculoskeletal systems in the elderly・ Elucidate pathological conditions and find therapeutic strategies for extremity, spine, soft tissue and bone tumor, & osteoporosis・ Offer new treatments for elderly patients・ Show a bright future for child patients with musculoskeletal disorders・ Provide excellent quality of life (QOL) for people through sports and exercise▶Divisions: 1. Upper Extremities Group 2. Lower Extremities Group 3. Spine Group 4. Oncology Group 5. Rheumatoid Arthritis・Osteoporosis Group・Please refer to each group page・ We tend to publish about 20 English papers per year, but we have published over 30 papers per year in recent years.Orthopaedic SurgerySmall but outstanding group with unique research achievementsTranslating Clues from Clinical Practice into the Research FieldUpper Extremities Group（Chief: Senior Assistant Prof. Masanori Hayashi ）Orthopaedic SurgerySummary of ActivityUpper extremity surgery is a field aimed at restoring the function of upper ex-tremities that are injured by trauma or disease. Our group takes clues from our clinical practice and translates them into research with wide-ranging themes. In order to share our research with the world, we present at international confer-ences and submit papers to international journals, particularly on the diagnosis and treatment of peripheral nerves, tendon rupture, arthritis, elbow disease, tenocyte differentiation, and stenosing tenosynovitis.・ Development of a surgical procedure for the elbow joint ・ Cohort study of Obuse resident (Obuse study)・ Study on imaging findings and postoperative results of peripheral neuropathy・ Development of tendon suture and transplantation methods ・ Elucidation of the tenocyte differentiation and tenosynovitis onset mechanism・ Application of results from research to the practical treatment of patients・ New preventative measures against geriatric diseases, such as locomotive syndrome and osteoporosis・ The mechanism of tenocyte differentiation and onset of tenosynovitis can be applied to the development of regenerative therapy and new treatment.Through research, you can deepen your knowledge of diseases related to upper limb sur-gery. Developing a keen eye for multifaceted phenomena will be useful for future clinical practice and further research.Research subjectOutlook for researchOutlook for students after graduationPhotograph taken during tendon transfer surgery Flexor tendon of Lubrisyn knockout mouseInduction of tenocyte differentiation by myostatinhttp://www.shinshu-u.ac.jp/faculty/medicine/chair/i-seikei/default.html051015202530354045502009101112131415161718