信大医学部医学科研究紹介2019（英語版）

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27advanced care for the patientsCardiovascular Surgery（Chief: Associate Prof. Tatsuichiro Seto）SurgerySummary of ActivityWe are conducting surgical treatment for cardiovascular diseases, peripheral vascular diseases including venous and lymphatic vessels, from heart disease to peripheral organs in the body as a whole. Particularly in multidisciplinary therapy for patients with severe systemic complications, elderly patients, patients with complex lesions, taking advantage of the university hospital, we offer medical treatment aiming for safer and more reliable surgery considering the patient’s long-term prognosis.・ Research and development of cardiac regenerative therapy using iPS cell.・ Research and development of surgery for thoracoabdominal aneurysm.・ Research and development of novel site-selective ischemic disease therapeutic using recombinant bifidobacteria・ Research and development of cardiac allograft rejection In medicine, it is said that today’s contraindications are tomorrow’s indications.Things that are forbidden today because something cannot be overcome may be permitted tomorrow thanks to just one breakthrough.We run practical training programs with specific goals that include understanding all charged cases and diseases, learning basic surgical procedures, and improving presentation tech-niques.Research subjectOutlook for researchOutlook for students after graduationState of cardiac surgeryCardiac regenerative therapy using iPS cell.“Modified from Shiba, et al. Nature 2016; 538: 388-391.”novel site-selective ischemic disease -teriaTo be specialists in Breast/（Chief: Prof. Ken-ichi Ito）SurgerySummary of ActivityThe division of breast, endocrine and thoracic surgery is in charge of two clinical departments—breast and endocrine surgery, and thoracic surgery. We mainly provide surgical care for tumors, including breast cancer, lung cancer, thyroid cancer, and mediastinal tumors. In our division, we strive to train “academic surgeons” who can provide treatment based on a scientific understanding of tumors, and have devoted ourselves to basic medical research on tumors.・ Analysis of oncogenesis and acquisition of malignant phenotype in thyroid, lung, and breast cancer.・ Mechanisms of cytotoxic drug resistance in breast and lung cancer・ To be specialists of breast/endocrine and thoracic surgery.・ To be “academic surgeons” who have the creativity they need to thrive on the global stage.Having clinicians engage in research while young prepares them to face the questions and problems they experience in the clinic, let us show the world the clinical and research suc-cesses made at Shinshu!Research subjectOutlook for researchOutlook for students after graduation【Upper】Thoracoscopic surgery【Lower】Robotic surgery【Upper】Endocrine surgery【Lower】Research in our labolatory【Upper】【Lower】【Upper】Expression of YB-1 in lung cancer tissue【Lower】Altertion of protein expression in breast cancer cells⬅⬅