信大医学部医学科研究紹介2019（英語版）

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13Structural and Functional Restoration of Damaged Organs Using Stem CellsSummary of ActivityHuman embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are attractive tools in regenerative medicine be-cause of their unlimited self-renewal and un-equivocal differentiation ability towards most somatic cell types. Our lab has a major focus in stem cell biology and its application, where we aim to provide novel therapies for refractory diseases. ・ Preclinical transplantation study of ES or iPS cell-derived cardiomyocytes for cardiac repair・ Generation of stem cell-derived biological pacemakers for cardiac bradyarrhythmias・ Establishment of novel treatments for muscular dystrophy by combining cell and gene therapiesDespite the remarkable progress in medical technology, there are still many patients who suffer from refractory diseases that require organ replacement. Regenerative medicine is an attractive alternative therapy for this. Our mission in this field is to study stem cell biology and clarify the feasibility of using stem cells for organ repair to provide effective, life-chang-ing treatments in the future. Research subjectOutlook for researchRegenerative Medicine（Chief: Prof. Yuji Shiba）Our team members working with stem cells in the cell culture roomMaster’sProgram Graduate School of Science and TechnologyDepartment of Biomedical EngineeringDoctorate ProgramDepartment of Biomedical EngineeringPhD in Medical Science, Biomedical EngineeringDepartment of Medical Sciences (PhD in Medical Science)International fellowshipMedical Doctor Bio-companiesAcademic institutesHospitalsOutlook for studentsafter graduationHow to improve clinical practice?— The answer is: EDUCATION!Summary of ActivityMedical education in the 21st century has rapidly modernized: from experi-ence-based to theory-based, and from spoon-feeding lectures to collaborative task-based activities in view of social constructivism.With its educational activities and relevant research, Center for Medical Educa-tion and Clinical Training contributes to filling the academic and practical need for clinical providers and leaders in the health professions. ・ Perceptions of health professions who are involved in outreach activities・ Curriculum reform and its influence on students・ Innovative collaborative/active learning approaches・ Educational assessment procedures for clinical clerkship・ We innovated a blended group learning and implemented it into a preclinical curriculum. It improved students’ motivation.・ We clarified tutors’ perceptions in an outreach activity program.・ We developed a test management system by collaborating with a company.By achieving fundamental knowledge on medical education, you will be able to analyze your educational activities, and revise them.You will achieve quantitative and qualitative research methods.Research subjectOutlook for researchOutlook for students after graduationMedical Education and Community Medivine（Chief: Prof. Tsuyoshi Tada）The interprofessional education program by means of group work and roll play.Graduate students can conduct research at various professional development stages; early exposure, preclinical, clinical, postgraduate, and continuous development.