工学部_研究紹介_2020_英語版

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Artificial Membrane for Cell-Like MicrochemicalSystemsYukihisaOkumuraAbiologicalcellisanextremelysophisticatedmicrochemicalsystem.Thisfacthasledscientiststoconstructacell-likemicrochemicalsystembyhumanhands.Forthesystem,artificialplasmamembranesareessentialastheyseparatetheinnerworldfromtheoutsideandbecometheinterfacebetweenthetwoworlds.Ourresearchgroupstudieslipidmembranevesiclesthathavethesizecomparabletobiologicalcells(giantliposomes)assuchartificialcellmembranes.Theconstructionofasophisticatedartificialcellwillbeoneofthemajorscientificandtechnologicalachievements.Althoughthereclearlyisalongwayahead,manyresearchgroupsaroundtheworldhavebeenworkingontheproblem.Thetechnology,ifestablished,willbeusedinmanybio-relatedfields,suchasmedicineandagriculture.Anexampleofpossibleapplicationsisadrugdeliverysystemmoreefficientandcompatibletohumanbodies.ProfessorChemistry of artificial lipid membrane vesicles (liposomes)Bio-mimetic microchemicalsystems.Working with giant vesicles. Giant vesicles are as large as biological cells and can be directly observed on an optical microscope.Micromanipulation of a giant vesicle. Various substances may be introduced into the vesicle by microinjection through a hollow needle.Manygraduatesfoundtheircareersinvariouschemistry-relatedfieldsincompanies.Throughthesisworks,studentsinourgroupareexpectedtoimprovetheskillsnecessaryasanengineer;carefulobservation,logicalthinkingandgoodresearchplanning.In the FutureAfter GraduationMaterialsChemistryColloidalmaterialsandtheirorganizationonsubstratearestronglyrequiredforrecentdevicefabricationbecauseofthedeviceminiaturization.Furthermore,theimprovementofdeviceperformanceisrequiredfortheconvenienceofourdailylife.TheSakai’sresearchgroupattemptstodevelop“high-puritycolloidalmaterials”becausetheyareexpectedtoexhibithigherperformance.Toshio SakaiSakai’sresearchaimstodevelopthemethodologiesforfabricationofthecolloidalmaterials(e.g.,metalnanoparticles,porousmaterials,emulsions,bubblesandfoam)andorganizationcolloidalmaterialsintomulti-dimensional(1D,2Dand3D)structuresinsolutionsand/oratinterfacesinanefficientmannerwithrespecttocost,energyandenvironment.Inparticular,amphiphiliccharacters(dualnatures)ofmoleculesorpolymersareessentialelementsfordesigningthemethodologies.ProfessorGenesis Research Institute, Inc., The State University of New York, Tokyo University of Science and ShinshuUniversity.Colloid and Interface Science.Preparation and characterization of colloidal materials such as metal nanoparticles, porous materials, emulsions, bubbles and foam.Colloid and Interface Sciencefor Beauty and HealthOptical micrograph of oil-in-water (O/W) emulsion..Emulsions are used in various fields such as cosmetic, food and medical field.Technologicalprocessessuchaspapermaking,potterymakingandthefabricationofsoaps,cosmeticsandmedicinesinvolvemanipulationofcolloidalsystems.Colloidandinterfacescienceprovidesvariousopportunitiesintheindustriessuchascatalyst,electronics,toiletryandmedicalfields.O/WIn the FutureAfter GraduationMaterialsChemistry9