Laboratory of Microbe-Plant Interactions Hiroki IRIEDA Assistant Professor, Ph.D. Fungus-plant interactions Anthracnose disease Colletotrichum Chloroplast dynamics Effector Plant pathogenic fungi are responsible for 70-80% of all known plant diseases. Thus, plant protection especially from fungal pathogens is a very critical problem for human society. Laboratory of Microbe-Plant Interactions is focusing on the pathosystems between Colletotrichum fungi, causal agents of anthracnose diseases, and their host plants. Understanding the molecular mechanisms underlying fungal pathogenicity and plant defenses will support development of new methods for disease control and prevention. A B C D A B C To successfully infect a plant, fungal pathogens (e.g. Anthracnose fungi) suppress host immunity. Cucumber leaf infected by C. orbiculare (left). Fungal hypha labelled with green fluorescent protein in biotrophic invasive stage (right). Novel chloroplast response induced by non-adapted Colletotrichum fungi in plant epidermis. Molecular basis of infection strategy in plant pathogenic Colletotrichum fungi. Biotechnology Division Development of new methods for control of anthracnose diseases. 33 Laboratory of Applied Reproductive Science Ikuo TOMIOKA Assistant Professor, Ph.D. Keywords: Animal Reproduction, Assisted Reproductive Technique (ART), Reproductive Technology, Gene Engineering, Neuro Science, Food Science. Our laboratory has the following ongoing projects: 1. Development of novel reproductive techniques relating to in vitro folliculogenesis, IVM/F/C, and ES/iPS cells. 2. Generation of animal models for human disease using transgenic and gene modifying techniques. 3. Discovering the functional food ingredients which have anti-aging effects on somatic stem cells. 1. Development of novel reproductive techniques. In vitro growth of isolated ovarian follicles is an emerging technology for fertility treatment. Novel reproductive techniques will provide solutions for the problem of infertility in human and poor reproductive efficiency in domestic animals. D C Fig. 1. Microscopy with micromanipulator (left) and manipulation of mammalian embryo (right). Fig. 2. Common marmoset (left) and its embryonic stem cells (upper right), induced pluripotent stem cells (lower right). Biotechnology Division 2. Generation of animal models for human disease. In medical research, many kinds of transgenic animals have been produced to model human disease and they provide indispensable tools for studying disease mechanisms and therapies in vivo. 3. Discovering the functional food ingredients. To maintain our health, preventive medicine has attracted a lot of attention in recent years. The one of most important factors in preventive medicine is food environments. Discovering the functional food will contribute to human health.
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