医学科研究紹介_2017-2018_英語版
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30spinal disease and deformity to the worldSpine Group(Chief: Associate Prof. Jun Takahashi)Orthopaedic SurgerySummary of ActivityThe Shinshu University Spine Group was one of the first university hospital re-search teams to introduce the navigation system to spinal surgery in 1996, and has since published many articles in English on surgery using the navigation system. We have also performed basic research on scoliosis and endoscopic spinal surgery utilizing 3D printers, in collaboration with associate Prof. Michihiko Koseki of the faculty of textile science and technology at our university. New and less-invasive surgical procedures for scoliosis, and the S-line (Shinshu-line), a new indicator for fusion area, have also been studied. In addition, joint clinical research on lumbar intervertebral fusion with Yamanashi University and Hama-matsu University School of Medicine is ongoing, as is joint research on musculo-skeletal epidemiology with our rehabilitation department.・Stress simulation for scoliosis correction・New surgical treatment for early onset scoliosis・ New surgical treatment strategy using the “S-line (Shinshu-line) ” for adolescent idiopathic scoliosis・Relationship between spine sagittal plane alignment and motor function/cognitive function・Development of safer and less-invasive surgery for scoliosis・Determination of optimal fusion area by the type of curve in adolescent idiopathic scoliosis・Facilitation of a longer, healthy life expectancy in a super-aging societyOrthopedic surgeons are fully trained in the diagnosis and treatment of spinal diseases, in-cluding deformities and trauma.These specialists can perform cutting-edge research anywhere in the world. Research subjectOutlook for researchOutlook for students after graduationPosterior Spinal Fusion Using Multi-Level Registration MethodSkip Pedicle Screw Fixationfrom rare cancers(Chief: Munehisa Kito, Clinical Assistant)Orthopaedic SurgerySummary of ActivityCancers in the orthopedic field are often called “rare cancers” because of their low frequency of occurrence and small number of cases. As a result of their rari-ty, the development of diagnostic / therapeutic methods is still lagging, and many patients face unfortunate consequences. Shinshu University is engaged in the development of new therapeutic agents for malignant bone tumors, methods to efficiently deliver anticancer agents o tumors, and new diagnostic criteria for ma-lignant soft tissue tumors. In the clinical field, we are studying bone morphology evaluation using CT images for the prevention of pathological fractures due to bone metastasis and lower limb muscle strength, in addition to the prediction of postoperative function in patients with malignant soft tissue tumors.・Development of new drugs for malignant bone tumors・Analysis of sugar chain-related gene expression in malignant soft tissue tumors ・Evaluation of bone morphology using CT images・ Lower limb muscle strength and predictive postoperative function of patients with malig-nant soft tissue tumorsCancer research in the orthopedic field is relatively underdeveloped compared to other areas of oncology, and research themes remain abundant. By establishing new therapeutic drugs and treatment systems, we can still help to “create the future” of patients suffering from can-cer.Because few doctors specialize in orthopedic oncology, learning in this group can provide the potential for you to become an expert in both research and clinical fields. You can aim to become doctors and researchers who can be actively engaged with the world.Research subjectOutlook for researchOutlook for students after graduationGraduate students studying on a daily basis for the development of new therapeutic drugsBone morphology analysis using CT im-ages to predict fracture riskStudy of Scoliosis Correction Stress Sim-ulationMuscle force measurement using hand held dynamometer/isokinetic dynamome-ter

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