農学部研究紹介英語版2018-2019

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Laboratory of Molecular Biotechnology Tasuku OGITA Assistant Professor Key word ・Food immunology ・Functional food science ・Intestinal microbiota ・Probiotics ・Fermented food It is thought that exchange of intestinal microbiota acts as a key factor in health maintenance and promotion. The intestinal microbiota was thought to be a key factor related to the bioregulatory function of food. Hence, we focused on identifying food contributing to health maintenance and promotion by studying the change in intestinal microbiota via intake of food. Effect of functional food on intestinal microbiota A B C D A B C Evaluation of the bioregulatory function of food to elucidate the mechanism underlying this function. Hypoxia cell culture system (A） Analysis of intestinal microbiota by DGGE（B） Biotechnology Division Immunomodulatory function of probiotics (A） (B） Analysis of immune cellAnalysis of intestinal microbiota Immunohistological analysisAdipose tissueIntestinal tissueTo elucidate the mechanism underlying the bioregulatory function of foodEvaluation of bioregulatory function in in vitro and in vivoLaboratory of Microbe-Plant Interactions Hiroki IRIEDA Assistant Professor Fungus-plant interactions Anthracnose disease Colletotrichum Chloroplast dynamics Effector Plant pathogenic fungi are responsible for 70-80% of all known plant diseases. Thus, plant protection especially from fungal pathogens is a very critical problem for human society. Laboratory of Microbe-Plant Interactions is focusing on the pathosystems between Colletotrichum fungi, causal agents of anthracnose diseases, and their host plants. Understanding the molecular mechanisms underlying fungal pathogenicity and plant defenses will support development of new methods for disease control and prevention. A B C D A B C To successfully infect a plant, fungal pathogens (e.g. Anthracnose fungi) suppress host immunity. Cucumber leaf infected by C. orbiculare (left). Fungal hypha labelled with green fluorescent protein in biotrophic invasive stage (right). Novel chloroplast response induced by non-adapted Colletotrichum fungi in plant epidermis. Molecular basis of infection strategy in plant pathogenic Colletotrichum fungi. Biotechnology Division Development of new methods for control of anthracnose diseases. 34