農学部研究紹介2017-2018_英語版

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13Laboratory of Animal Developmental GeneticsHiroshiKAGAMIProfessor&JSPSP.O.Keywords;AnimalStemCellBreedingOrganRegenerationBiotechnologyRecently,wehavedevelopedthenovelstrategiesforavianbiotechnologyusingpluripotentstemcellsandgermcells.Thesestrategieswillbeamongthemostpowerfultoolsforfuturepoultrybreeding.*Developmental regulation of avian stem cellsABCDABCDivision of Animal Science*Use of avian eggs as bioreactors*A novel system for poultry breedingNovel strategies to manipulate avian embryos.Invited seminar in an International Meetingfor stem cell manipulation. Laboratory of Molecular Cellular BiologyTomohideTAKAYAAssistant Professor-Stem cell biology-Skeletal muscle-Myogenic differentiation-Regenerative medicine-Transcription factorMuscledistinguishesanimals.Wecanmoveaswewantbymusclefunctions.Higheranimalshavethreetypesofmuscles;cardiac,smooth,andskeletalmuscles.Ourmovementscanberealizedbycooperationofthreemuscles.Thesemusclecellsareverysimilar,inthesameway,quitedifferent.Oneofourinterestsisthemechanismwhichenablesmusclediversity.Forhealthylongevity,allmusclesshouldbemaintainedhealthful.Wearechallengingtounderstandthemolecularandcellularmechanismsofmusclularhomeostasis,regeneration,anddiseases.ABCDABCImmunostainingofskeletalmusclestemcellsduringmyogenicdifferentiationinculture.Bioinformaticanalysisofthegenome-wideDNA-bindingsitesofmyogenictranscriptionfactors.Division of Animal ScienceWearefocusingonskeletalmusclestemcells,satellitecells,whichenablerobustregenerativecapacityofskeletalmuscle.Oursubjectsare;1.Researchofthemechanismofskeletalmuscleregeneration.2.Developmentofthefoodsanddietstopreventmusclediseases.3.Establishmentofthetechnologyforartificialmuscleandmeat.Ourresearchisgoingonthefieldsofagriculturalbiological,andmedicalscienceswiththefinetechniquesofstemcellbiology.Day 0Day 1Day 2Day 3