The effects of mechanical force during physical exercise on blood coagulation and fibrinolysis were investigated and the influence of sports shoes on it was also studied.
　When the mechanical vibration was loaded on the human palm as a model of the mechanical force during physical exercise, the blood fibrinolytic activity was elevated, though the essential clinical laboratory parameters of blood coagulation were not changed.
　The tissue plasminogen activator was released from vessel endothelial cells which were located in the vibration-loaded palm. The effects of mechanical force on the sole of feet were experimented by loading the side-step test with bare feet. The with blood coagulation factor VIII related antigen were released from the local vessel endothelial cells as well as the tissue plasminogen activator. When the same loading on feet with sports shoes was performed, they did not change so much. These findings indicate that the materials and shape of sports shoes have influence on the effects of mechanical force on human body during physical exercise. Effect described above must be considered when the sporting requisites are developed.

DESCENTE SPORTS SCIENCE Vol.8/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE