Effect of Habitual Physical Activity on Cardiovascular Response to Exercise and Plasma Catecholamine and Urinary Kallikrein in Middle-Aged Women with Family History of Hypertension
【Supercategory：7. DESCENTE SPORTS SCIENCE Subcategory：7.9 Vol.9】
Purposes of present study were to evaluate the effect of habitual physical activity on cardiovascular response to submaximal exercise and plasma catecholamine and urinary kallikrein concentration in middle-aged women with family history of hypertension (n=9; 40.6±4.0 yrs). First study was performed at January '87. At this time, all subjects performed regularily endurance training in training center. Second study was performed at October '87 to clarify the effect of detraining. Of all subjects, 5 subjects were continuously trained (A group; 40.2±4.4 yrs), and 4 subjects were stopped training after 1st study (B group; 41.0±3.0 yrs). Base-line study was performed prior to start of endurance training.
1) After training, we found significant increase in VO₂, max and significant reductions in triglyceride in B group. At second study, A group was keeping same level as 1st study, while B group returned to base-line level. Significant correlation coefficient found between ⊿triglyceride and ⊿VO₂max after training and detraining in B group.
2) After detraining, blood pressure response to submaximal exercise in B group was in the same level as 1st study.
3) Resting blood pressure in A group was stable throughout the experimental periods. Two subjects of B group had SBP greater than 140 mmHg at base-line level. Blood pressure was decreased within normotension after training and returned to base-line level after detraining. Especially, one subject of B group was shift in borderline hypertension after detraining. Urinary kallikrein (UK) concentration in B group was lower than A group, but not significant. Plasma nor-adrenaline concentration in B group increased slightly after detraining.
4) At 2nd study (Oct. '87), we measured UK response to maximal exercise. UK concentration in both groups increased significantly after maximal exercise and increasing rate of UK was higher in B group as compared with A group.
The present results suggest the effectiveness of long-term aerobic training in stabilization and or improvement of blood pressure and blood lipids of peoples with family history of hypertension.
DESCENTE SPORTS SCIENCE Vol.9/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
1) After training, we found significant increase in VO₂, max and significant reductions in triglyceride in B group. At second study, A group was keeping same level as 1st study, while B group returned to base-line level. Significant correlation coefficient found between ⊿triglyceride and ⊿VO₂max after training and detraining in B group.
2) After detraining, blood pressure response to submaximal exercise in B group was in the same level as 1st study.
3) Resting blood pressure in A group was stable throughout the experimental periods. Two subjects of B group had SBP greater than 140 mmHg at base-line level. Blood pressure was decreased within normotension after training and returned to base-line level after detraining. Especially, one subject of B group was shift in borderline hypertension after detraining. Urinary kallikrein (UK) concentration in B group was lower than A group, but not significant. Plasma nor-adrenaline concentration in B group increased slightly after detraining.
4) At 2nd study (Oct. '87), we measured UK response to maximal exercise. UK concentration in both groups increased significantly after maximal exercise and increasing rate of UK was higher in B group as compared with A group.
The present results suggest the effectiveness of long-term aerobic training in stabilization and or improvement of blood pressure and blood lipids of peoples with family history of hypertension.
DESCENTE SPORTS SCIENCE Vol.9/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
| Researcher | Shuzo Kumagai, Naoko Emura, Yoshiaki Kondo, Masahiro Nishizumi |
|---|---|
| University or institution | Department of Community Health Science, Saga Medical School |
Keywords
habitual physical activity, cardiovascular response, plasma catecholamine, urinary kallikrein concentration, middle-aged, hypertension