The Effects of Physical Exercise on Immune Function
【Supercategory：7. DESCENTE SPORTS SCIENCE Subcategory：7.9 Vol.9】
The purpose of this investigation was to determine the relationship between physical training and host-defense mechanisms.
Untrained healthy subjects underwent 30-min acute exercise of moderate intensity corresponding to anaerobic threshold on a bicycle ergometer. Cellular immunity was examined prior to, immediately after, and 30-min after exercise.
Immediately after exercise a significant increase was observed in the number of white blood cell and granulocytosis.
OKT4-positive cell (helper/inducer) to OKT8-positive cell (suppressor/cytotoxic) ratio was reduced significantly, there by implying that acute exercise suppresses B lymphocyte function.
Natural Killer-cell activity, however, increased immediately after exercise. This may indicate that exercise acutely stimulates both cytotoxicity to tumour cells and body's natural defensibility to virus.
We suggest that though various reactions on cellular immune function are brought about by acute exercise, host defense ability is maintained throughout and after exercise.
DESCENTE SPORTS SCIENCE Vol.9/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
Untrained healthy subjects underwent 30-min acute exercise of moderate intensity corresponding to anaerobic threshold on a bicycle ergometer. Cellular immunity was examined prior to, immediately after, and 30-min after exercise.
Immediately after exercise a significant increase was observed in the number of white blood cell and granulocytosis.
OKT4-positive cell (helper/inducer) to OKT8-positive cell (suppressor/cytotoxic) ratio was reduced significantly, there by implying that acute exercise suppresses B lymphocyte function.
Natural Killer-cell activity, however, increased immediately after exercise. This may indicate that exercise acutely stimulates both cytotoxicity to tumour cells and body's natural defensibility to virus.
We suggest that though various reactions on cellular immune function are brought about by acute exercise, host defense ability is maintained throughout and after exercise.
DESCENTE SPORTS SCIENCE Vol.9/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
| Researcher | Hiroyo Kitao*1, Takashi Yamada*2, Ichiro Kono*3, Kiyoji Tanaka, Shiro Kuwajima*2, Fumio Nakadomo*1, Mitsuo Matsuda*3, Kazuya Maeda**2 |
|---|---|
| University or institution | *1 Osaka Prefectural College of Nursing, *2 Osaka City University, *3 University of Tsukuba |
Keywords
physical training, host-defense mechanisms, lymphocyte function