Mechanism of Antihypertensive Actionin Exercise Therapy -Developmentofan Apparatus System to Determine Force-Arterial Pressure-
【Supercategory:7. DESCENTE SPORTS SCIENCE Subcategory:7.25 Vol.25】
They performed IHG at intensities of 12.5%, 25%, 37.5%, 50%, 62.5%, and 75% of maximum voluntary contraction (MVC) in a sitting position. IHG was measured in ten seconds of each percentage continuously, and was completed within 1 minute through all intensities. Cardiac output and arterial blood pressure were recorded on beat-by-beat basis during the IHG. The adequate data were gathered from 12 subjects, therefore the data analysis was carried out on the data of these 12 people. The systolic (SBP) and diastolic (DBP) blood pressures increased with intensity of exercise in a similar manner with the mean blood pressure (MBP) changes, in both groups. The arterial blood pressure response (CF-AP) during IHG was determined as the blood pressure change (△AP/Force) from 25% MVC to 62.5% MVC. It was indicated that CF-SBP, -DBP and -MBP were higher in MO group (n=6) than in Y group (n=6) and that the difference between both groups at CF-SBP was more remarkable than at CF-DBP and -MBP, but not significant. Cardiac output at rest in MO group resulted lower than in Y group, and significant changes were not observed during IHG in both groups. Total peripheral resistance (TPR) at rest was significantly higher in MO group than in Y group. TPR during IHG in Y group significantly increased at 75% MVC, and that in Mo group showed significant increase at 62.5% and 75% MVC.
These results suggest that pressor response (CF-AP) during IHG was influenced by age due to the elevation of peripheral vessel resistance. It was concluded that the apparatus system developed in this study might have possibilities to clarify the factor of blood pressure response during IHG. It was also suggested that it is necessary to develop an apparatus which can measure more stable values of artery blood pressure and cardiac function on beat-by-beat basis during IHG, and to devise appropriate measurement conditions.
DESCENTE SPORTS SCIENCE Vol.25/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
Researcher | TetsuyaSeino*1, Masato Suzuki*2, Masamichi Sudoh*3, Kuninobu Yokota*4 |
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University or institution | *1 Kisarazu National College of Technology, *2 Department of Laboratory Medicine, The Jikeikai University School of Medicine,*3 Division of Aerospace Medicine, Department of Physiology 2, TheJikeikai University School of Medicine,*4 Department of Internal MedicineⅢ, The Jikeikai University School of Medicine |
Keywords
blood pressure, cardiac function, isometric incremental handgrip exercise, vessel resistance, arterial blood pressure response, peripheral vessel resistance