Effect of Frequency and Duration of Exercise on Cellularity of Adipocyte and Secretion of Adipocytokines
【Supercategory：7. DESCENTE SPORTS SCIENCE Subcategory：7.29 Vol.29】
The purpose of this study was to investigate the optimal weight reduction program for dietary and exercise therapy. We tested about the rate of weight reduction arranged by voluntary wheel running protocol that will effect on the cellularity of adipocyte and secretion of adipocytokines.
Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an animal model of hyperphagia and obesity, was used in this study (n=12, 19-week-old at the end of experiment). The rats were randomly assigned to either the 2 (17 to 19-week-old, everyday) or 4 (15 to 19-week-old, about every two day) weeks voluntary exercise or control group. The exercise frequency and duration were arranged, and all rats weighed about 85% of control rats at the end of experiment.
Compared to 2 weeks exercise, 4 weeks exercise promoted the downsizing of adipocyte and provided a weak reduction in the value of blood adiponectin concentration. These results suggested that the low frequency and long duration exercise therapy is more effective for the cellularity of adipocyte and maintenance of blood adiponectin concentration compared to the high frequency and short duration exercise therapy.
DESCENTE SPORTS SCIENCE Vol.29/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an animal model of hyperphagia and obesity, was used in this study (n=12, 19-week-old at the end of experiment). The rats were randomly assigned to either the 2 (17 to 19-week-old, everyday) or 4 (15 to 19-week-old, about every two day) weeks voluntary exercise or control group. The exercise frequency and duration were arranged, and all rats weighed about 85% of control rats at the end of experiment.
Compared to 2 weeks exercise, 4 weeks exercise promoted the downsizing of adipocyte and provided a weak reduction in the value of blood adiponectin concentration. These results suggested that the low frequency and long duration exercise therapy is more effective for the cellularity of adipocyte and maintenance of blood adiponectin concentration compared to the high frequency and short duration exercise therapy.
DESCENTE SPORTS SCIENCE Vol.29/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE
| Researcher | Masaki Kimura*1, Tomokazu Shinozaki*1, Makoto Hosoyamada*1, Masato Suzuki*2, Hideki Yamauchi*2 |
|---|---|
| University or institution | *1 Kyoritsu University of Pharmacy, *2 Jikei University, School of Medicine |
Keywords
weight reduction, dietary, exercise therapy, adipocytokines, hyperphagia, obesity