ABSTRACT

　The aim of the present study was to determine the effects of aerobic exercise with different pattern of blood flow restriction on endothelial function of the non-active limb. Six males （25 ± 3 yr, 176.1 ± 5.5 cm, 66.2 ± 6.6 kg） completed 30 min of recumbent leg-cycling at 40% of V･O2peak in two trials: 1） exercise with continuous blood flow restriction （continuous trial） and 2） exercise with intermittent blood flow restriction （3 cycles of 5 min inflation/5 min deflation） （intermittent trial）．Cardiovascular hemodynamics and brachial shear rate were recorded every five min during exercise. Brachial artery flow-mediated dilation （FMD） was assessed before exercise and 10 and 60 min post-exercise. Both trials showed increases in arterial blood pressure during exercise, with the intermittent trial demonstrating lower values during the deflation phases（10, 20, and 30 min） compared to the continuous trial（p<0.001）．Changes in blood flow and shear rate during exercise did not differ between the trials （p>0.05）．FMD was decreased in both the continuous （7.7 ± 1.2 to 3.7 ± 1.4%）and intermittent （8.0±2.0 to 4.9±1.6%） trials at 10 min post-exercise （p<0.001）．However, the change in FMD from baseline to 60 min post-exercise was higher in the intermittent trial（+1.7±2.5%） than in the continuous trial（-3.1±1.0%, p = 0.047）．In conclusion, impaired vascular function following exercise with blood flow restriction can be restored with using intermittent blood flow restriction, independent of shear rate kinetics.

DECENTE SPORTS SCIENCE Vol.46/The DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE