ABSTRACT

　It is reported that low carbohydrate diet blunts insulin secretion in response to glucoseload via reduced SGLT1 in the small intestine. This adaptation may be a disadvantageousfor athletes to recover muscle glycogen and protein synthesis after an exercise bout. Thepurpose of the present study is to examine the effects of low carbohydrate diet on muscleglycogen recovery and protein synthesis after an acute bout of exercise. Six-week oldC57BL/6 male mice were trained by means of voluntary running wheel for 6 weeks, thendivided into two groups, control diet（ CON） and low carbohydrate diet（ LC）．The micewere fed respective diet for 2 weeks and continued running training. After 2-week dietintervention, all mice were subjected to 30-min treadmill running, then immediately aftercessation of running, mice were administrated glucose solution （2 g/kg body weight）．Muscle and small intestine were dissected out 2 h after glucose administration. Muscleglycogen concentration and SGLT1 protein content in small intestine in the LC groupwere lower than those in CON group. However, phopsho-p70S6K protein content did notdiffer between groups. These results suggest that a low carbohydrate diet feeding delaysmuscle glycogen recovery after an exercise bout.

DECENTE SPORTS SCIENCE Vol.40/The DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE