ABSTRACT

　Growing evidence has shown that certain biogenics produced during fermentation of milk could have physiological benefits. In a placebo-controlled double blind experimental design, we investigated the effect of a biogenic factor, milk casein hydrolysate, derived from lactobacillus fermented milk on muscle damage and glucose metabolism after exercise in middle-aged to elderly people. Ten middle-aged to elderly subjects (49±2yr) participated in each of two trials of the study: exercise with placebo (placebo trial) and exercise with milk casein hydrolysate (active trial). Participants carried out downhill walking (decline grade: -5%, speed: 5km/h, time: 30min). Test tablet (placebo or active) was taken before and after exercise in doubleblind method. On the next day of exercise, muscle damage and metabolic parameters were measured. Although muscle soreness was not difference between trials, plasma creatine kinase was significantly lower in the active trial than the placebo trial. In addition, carbohydrate oxidation after glucose administration was significantly higher in the active trial than the placebo trial. These observations suggested that intake of milk casein hydrolysate before and after low intensity exercise could improve glucose metabolism associated with suppressing delayed-onset muscle damage.

DESCENTE SPORTS SCIENCE Vol.38/THE DESCENTE AND ISHIMOTO MEMORIAL FOUNDATION FOR THE PROMOTION SPORTS SCIENCE