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教員氏名
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奥山 隆平
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所属・職名
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信州大学医学部皮膚科 教授
信州大学医学部メディカル・ヘルスイノベーション講座 教授(兼任)
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研究分野
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表皮細胞の分子細胞生物学、メラノーマの生物学
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研究紹介
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(1) シグナル伝達による表皮細胞やメラノーマ細胞の増殖制御
(2) メラノーマの遺伝子解析
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＜主な業績＞
- Minagawa A, Koga H, Uhara H, Yoshiharu Yokokawa Okuyama R. Age-related prevalence of dermoscopic patterns in acquired melanocytic nevus on acral volar skin. JAMA Dermatol in press.
- Ishikawa Y, Hosogane M, Okuyama R, Aoyama S, Onoyama I, Nakayama K, Nakayama K. Opposing functions of Fbxw7 in keratinocyte growth-differentiation and skin tumorigesis mediated through negative regulation of c-Myc and Notch. Oncogene 32: 1921-1932, 2013.
- Miyake T, Ogawa E, Mikoshiba A, Kobayashi A, Hosoe H, Kashiwabara S, Uhara H, Owada Y, Okuyama R. Epidermal-type FABP is a predictive marker of clinical response to systemic treatment and ultraviolet therapy in psoriatic skin lesions. J Dermatol Sci 68: 199-202, 2012.
- Ashida A, Uhara H, Kiniwa Y, Oguchi M, Murata H, Goto Y, Uchiyama A, Ogawa E, Hayashi K, Koga H, Okuyama R. Assessment of BRAF and KIT mutations in Japanese melanoma patients. J Dermatol Sci 66: 240-242, 2012.
- Sakaizawa K, Goto Y, Kiniwa Y, Uchiyama A, Harada K, Shimada S, Saida T, Ferrone S, Takata M, Uhara H, Okuyama R. Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level. British J Cancer 106: 939-946, 2012.