Meeting Young Researchers

Profile

Takeshi SHIMOSATO

Research Area:
Animal Science and Grassland Science , Food Science and Nutritional Chemistry , Applied Molecular Cell Biology
Keywords:
Food Immunology , Probiotics , DNA vaccine
Contact:
8304 Minami-Minowa-mura, Kamiina-gun, Nagano-ken
Japan 399-4598
URL:
http://karamatsu.shinshu-u.ac.jp/lab/shimolab/fiber/Home.html

Employment Experience:
Feb.2007-Oct. 2007:
National Cancer Institute at Frederick

Apr. 2006-Jan. 2007:
U.S. Food and Drug Administration

Apr. 2006-Oct. 2007:
Japan Society for Promotion of Science fellow for Research Abroad


Education:
Ph.D. Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan, March 2006

M.Sc., Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan, March 2003

B.S., Laboratory of Animal Products Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan, March 2001


Awards:
1. Award for Young Scientist from The Japanese Society of Animal Science (2011)

2. Animal Science Journal Excellent Paper Award 2008(2008)

3. The Best Presentation Award for the 103rd annual meeting of Japanese Society of Animal Science (2004)

4. Award for Young Scientist from The Japanese Society of Dairy and Food science (2005)

5. 2006 President's Award of Tohoku University (2006)

6. 2006 Dean's Award of Graduate School of Agricultural Science of Tohoku University (2006)


Selected Publications:
  • Shimosato T, Fujimoto M, Tohno M, Takashi Sato, Tateo M, Otani H, Kitazawa H, CpG oligodeoxynucleotides induce strong up-regulation of interleukin 33 via Toll-like receptor 9. Biochemical and Biophysical Research Communications. 2010. Mar; 394, 81-86.
  • Shimosato T, Tohno M, Sato T, Nishiura J, Kawai Y, Saito T, Kitazawa H, Identification of a potent immunostimulatory oligodeoxynucleotide from Streptococcus thermophilus lacZ, Animal Science Journal. 2009. 80,597-604
  • Shimosato T, Kimura T, Tohno M, Iliev ID, Katoh S, Itoh Y, Kawai Y, Sasaki T, Saito T, Kitazawa H., Strong immunostimulatory activity of AT-oligodeoxynucleotide requires a six-base loop with a self-stabilized 5'-C...G-3' stem structure. Cellular Microbiol. 2006, 8:485-95.
  • Shimosato T, Kitazawa H, Tohno M, Katoh S, Iliev ID, Nagasawa C, Kawai Y, Saito T., Augmentation of TH-1 type response by immunoactive AT oligonucleotide from lactic acid bacteria via Toll-like receptor 9 signaling. Biochem Biophys Res Commun. 2005, 326:782-787.
  • Shimosato T, Tohno M, Kitazawa H, Katoh S, Watanabe K, Kawai Y, Aso H, Yamaguchi T, Saito T., Toll-like receptor 9 is expressed on follicle-associated epithelia containing M cells in swine Peyer's patches. Immunol Lett. 2005, 98: 83-89.
  • Shimosato T, Kitazawa H, Saito T. Immunoactivity of DNA from immunobiotic lactic acid bacteria via Toll-like receptor 9 and potential applications. Milk Science. 2005, 54:9-15.