（Chief: Prof. Yuji Shiba）・ Preclinical transplantation study of ES or iPS cell-derived ・ Generation of stem cell-derived biological pacemakers for ・ Establishment of novel treatments for muscular dystrophy by combining cell and gene （PhD in Medical Science, Biomedical Engineering）12G1927A(G643S)Mother母親Infant子供FatherOthers他人Specific mutation found in sudden death cases among patients administered psy-chotropic drug therapy.父親Master’sProgram Graduate School of Science and TechnologyDepartment of Biomedical EngineeringMedical Doctor Doctorate ProgramDepartment of Biomedical EngineeringInternational fellowshipDepartment of Medical Sciences (PhD in Medical Science)Bio-companiesAcademic institutesHospitalsResearch subjectResearch subjectOutlook for researchOutlook for students after graduation・ DNA typing of degraded DNA samples・ Relationship between sudden death of elderly people and amyloidosis・ Molecular analysis in sudden death cases among patients administered psychotropic drug ・ Development of systematic analysis methods for poisoning substances・ Search for markers useful for investigating causes of deaththerapyWe have a great societal responsibility for the cause of death investigation. Developments in forensic research will lead to increase of the accuracy of the cause of death investigation. ・ Forensic physician・ Forensic technician engaged in DNA analysis or drug analysiscardiomyocytes for cardiac repaircardiac bradyarrhythmiastherapiesOutlook for researchDespite the remarkable progress in medical technology, there are still many patients who suffer from refractory diseases that require organ replacement. Regenerative medicine is an attractive alternative therapy for this. Our mission in this field is to study stem cell biology and clarify the feasibility of using stem cells for organ repair to provide effective, life-chang-ing treatments in the future. Our team members working with stem cells in the cell culture roomPaternity testingAmyloid deposition in the heart. Outlook for studentsafter graduationSummary of ActivityPersonal identity using the DNA typing has progressed rapidly in these last few decades. The problem with which forensic scientists have recently been con-fronted involves the technical difficulty of analyzing degraded DNA samples. Our main research field is the DNA typing of degraded DNA samples. Also, we are researching forensic pathology and molecular genetics in sudden death.Summary of ActivityHuman embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are attractive tools in regenerative medicine be-cause of their unlimited self-renewal and un-equivocal differentiation ability towards most somatic cell types. Our lab has a major focus in stem cell biology and its application, where we aim to provide novel therapies for refractory diseases. Regenerative MedicineLegal (Forensic) Medicine have a great societal responsibility for the cause of death investigationStructural and Functional Restoration of Damaged Organs Using Stem CellsLegal Medicine（Chief: Prof. Hideki Asamura）
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