繊維学部研究紹介_英語版
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53Department of Applied BiologyUsing insects’ high-performance sensors to develop methods for exterminationI am carrying out research on the sensors carried by insects to monitor the arrival of the seasons via sensor proteins that respond to temperature and day length. My findings can be applied to the extermination of pests and invasive species through such techniques as causing eggs to hatch in winter and making adult insects without wings grow them. This approach is garnering attention as a pest extermination method that does not harm nature or humans.Associate Professor Shiomi took his current position in 2007 after serving in the Faculty of Textile Science and Technology at Shinshu University as an assistant professor. His areas of research include environmental molecular entomology and applied entomology with a focus on the dormancy, metamorphosis, and seasonal morphology of insects.The ability to control the dormant stage of insects is useful not only for exterminating pests, but also for protecting ecosystems. Further, I believe that explaining the ecology of insects can contribute solutions for global environmental, food-related, and medical problems.Outlook for researchGraduates can nd employment at food and pharmaceutical companies, environmental companies working with nature, companies engaged in genetic analysis, and even trade-related inspection companies.Outlook for students after graduationHestina assimilis larva. There are many insects like this. Typically, students who gather in my lab are lovers of insects who see the appeal of their mysteries.A student observes cultured cells into which insect sensor genes have been inserted.Useful genes are cloned from insects of the order Lepidoptera.Kunihiro ShiomiAssociate ProfessorDepartment of Applied BiologyDesigning and applying useful proteins by studying the structure and function of proteinsI am carrying out research to gain a deep understanding of the structure and function of proteins and to design, develop, and apply useful modified and artificial proteins. Based on my goal of achieving results that will prove useful in addressing biological resource issues and environmental problems, my lab uses cutting edge chemistry to see, examine, create, and apply proteins.Associate Professor Arai took his current position in December 2007 after working as a researcher at RIKEN and Princeton University in the U.S. His areas of research are structural biology, which he uses to examine the three-dimensional structure and function of proteins, and protein engineering, which he uses to nd applications for proteins through their modication and design.My goal is to apply proteins in new elds, for example in pharmaceutical development and biotechnology, in order to create eco-friendly high-function nano-materials, clean chemistry catalysts, and high-sensitivity biosensors. In this way, I hope to contribute the achievement of a sustainable and abundant society.Outlook for researchGraduates are employed in numerous elds, including at pharmaceutical, enzyme, and chemical companies.Outlook for students after graduationSelf-assembling nano-architectures are created from a protein nano building block by fusing a dimeric de novo protein WA20 and a trimeric foldon domain from T4 phage. (Kobayashi, N., et al., J. Am. Chem. Soc., 137, 11285-11293, 2015)An experiment in the research lab (upper left), production of useful proteins with microorganisms (upper right), a protein crystal that shines like a precious stone (lower left), and an x-ray diraction experiment at a synchrotron radiation facility (lower right)Ryoichi AraiAssociate ProfessorBarrel 6-mer Tetrahedron 12-mer Self-assembly WA20-foldon M form model S form model WA20 dimer Foldon trimer Fusion Protein Nano-building Block (PN-Block)

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