Engineering-Research-Activity2016｜SHINSHU UNIV.

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Creation of Heterocyclic Compounds by Organic Cynthesis: Development of novel catalysts and highly selective reactionsSugaLabThereisasubtledeferenceamongchemicalstructuresthathastodowiththethree-dimensionalarrangementsofatomsinspace.Thesearrangementdifferinthewaythatarighthandandalefthanddiffer-thatistheyaremirrorimagesofeachother.Manymedicinalchemicalscanexistintwomirrorimageforms,anditisoftentruethatoneofthemisabettermedicineandtheothermayevenbeharmful.Inourlaboratory,wehavebeeninvestigatinganewmethodologyforthesynthesisofmedicinallyimportantopticallyactiveheterocycliccompoundswiththedesiredhandedness.Organicsynthesiscontributesnotonlyforthecreationofmedicinesandagrochemicalsbutalsoforthesynthesisoforganicmaterialssuchasorganicsemiconductors.Fortheorganicsynthesis,itisimportanttodevelopanefficientandselectivereactiontoaffordonlyadesiredproduct.Ourgoalistodevelopsuchnovelcatalystsforthereaction,whichwillcontributetoawiderangeofchemicalindustries.HiroyukiSugaProfessorofChemistryHe joined Shinshu University in 1998. His research interest is the synthesis of optically active heterocyclic compounds with biological activity. Organic compounds are synthesized by using several reagents, solvents, and glassware in a hood. Graduatesfrommylaboratorynowworkinpharmaceutical,agrochemical,andchemicalcompanies.Ourstudentscanapplytheirknowledgeoforganicchemistrytothefieldsofpolymersandevenotherchemicalmaterialsaswellasrelativelysmallorganicmolecules.Anorganicmoleculecoordinatestoacatalystanditisactivated.写真サイズ高さ4.35cm×幅3.6cm配置位置横15.3cm、縦2.85cm3DstructureofaproductisdeterminedbyNMR.Chemistry& MaterialEngineeringIn the FutureAfter GraduationApplicationofBiologicalFunctionforIndustrialFields as Green ChemistryOrganismsalwaysproducemanyproteinssuchasenzymeswhichdesignedbasedongenes.Enzymesworkascatalystsformostreactionsoccurringincellsoforganisms.Thevelocityofcatalyticreactionsbyenzymesareincrediblyrapidunderthecommontemperatureandpressure.Wecanapplythiseco-friendlyprocessforindustries,asasustainabledevelopmentrequiresgreen.OurLaboratoryisinterestedinthefundamentalissuessuchasproperties,structuresandfunctionsofenzymestoproducematerialsandmoleculesbyasustainableprocess.OurLabfocusesonthecarbohydrateswhicharesynthesizedbyphotosynthesisusingcarbondioxide.Celluloseisoneofmostabundantorganicsubstancesinbiosphere.Biomassstoresalargeamountofenergyinchemicallinkage.Weshouldusetheenergytoproducebiofuelsandmaterials.Chemistrycontributestoeveryfieldthatmanufacturingcompaniesworkon.Theyarechemical,electrical,foodcompanies.StudentsthathavegraduatedareactivelyworkingeverywhereinJapan.Yoshihiko AmanoGraduated from Shinshu University, PhD (1994, Shinshu University)2005-Professor of Faculty of Engineering, Shinshu University Major fields：Biological Chemistry (Enzymology, Carbohydrate Chemistry) Mushroomfungus,Irpexlacteusisolatedin1930sbyProf.Nisizawa.Thismicroorganismhasahighabilityfordegradationofwoodybiomass.Continuousflow-typehydrothermalreactorwedesigned:thisisapowerfultoolforprocessingorganicsubstancesfromplantbiomass.AmanoLabChemistry& MaterialEngineeringIn the FutureAfter Graduation40

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