Graduate School of Medicine Human Sciences
Preventive Medicine and Public Health



Professor: Tetsuo Nomiyama
Senior Assistant Professor: Teruomi Tsukahara

Summary of Activity
The goal of our research laboratory is to elucidate the mechanisms of human diseases using experimental and epidemiological methods, and to frame a policy for preventive medicine and public health. To this end, we have set ourselves three targets.

  1. Research activity
  2. *To apply the techniques of basic medicine and epidemiology to improve occupational and environmental health
    *Risk assessment for maternal and child health, mental health and infectious diseases
  3. Education
  4. *The nurturing of talented individuals who have the relevant skills in environmental and preventive medicine
    *To support doctors in community medical care who wish to use epidemiological techniques
  5. Social contribution
  6. *To make research results available in order to benefit society


Research Projects

The current projects in our laboratory are as follows:

Hygiene
*Japan Eco & Child Study (a subunit of the Koshin district center)
*Health effects of formaldehyde
*Health effects of fumigant (sulfuryl fluoride, ethylene oxide and propylene oxide)
*Dust mask assessments in occupational health

Public health
*Epidemiological study of Sleep Apnea Hypopnea Syndrome
*Child abuse prevention
*Development of devices using organic and inorganic nano-materials
*Socio-economic study of medical expenses
*Mental health for workers
*Epidemiological study of suicides

References
    Journal article

  1. Nishimura, S., Yasui, H., Miyauchi, H., Kikuchi, Y., Kondo, N., Takebayashi, T., Tanaka, S., Mikoshiba, Y., Omae, K., and Nomiyama, T. (2009) A cross-sectional observation of effect of exposure to N-Methyl-2-Pyrrolidone (NMP) on workers’ health. Ind Health 47: 355-362.

  2. Tsukahara, T., Washizuka, S., Fujimura, T., Hayashi, H., Tokuhara, S., Takeda, H., Kodama, K., Nishizawa, R., Fuse, M., Yuzawa, N., Matsusima, Y., Kamijo, K., Shimohara, A., Yamanaka, S., Nomiyama, T., and Kawa, S. (2008) Prevention and control of measles infection in Shinshu University. Campus Health 45: 191-196. (in Japanese)

  3. Nomiyama, T., Kikuchi, Y., Kumagai, N., Dekio, F., Uemura, T., Hosoda, K., Sakurai, H., and Omae, K. (2002) Short-term changes in cadmium in feces, blood and urine after dietary cadmium intake in young Japanese females. J Occup Health 44: 429-432.

  4. Nomiyama, T., Uehara, M., Miyauchi, H., Imamiya, S., Tanaka, S., and Seki, Y. (2001) Acute hepatic dysfunction induced by subchronic N,N-dimethylformamide exposure in the resin synthetic industry. Ind Health 39: 33-36.

  5. Nomiyama, T., Nakashima, H., Sano, Y., Chen, L. L., Tanaka, S., Miyauchi, H., Yamauchi, T., Sakurai, H., and Omae, K. (2001) Does the polymorphism of cytochrome P-450 2E1 affect the metabolism of N,N-dimethylformamide? Comparison of the half-lives of urinary N-methylformamide. Arch Toxicol 74: 755-759.

  6. Nomiyama, T., Nakashima, H., Chen, L. L., Tanaka, S., Miyauchi, H., Yamauchi, H., Sakurai, H., and Omae, K. (2001) N,N-dimethylformamide: Significance of dermal absorption and adjustment method for urinary N-methylformamide concentration as a biological exposure item. Int Arch Occup Environ Health 74: 224-228.

  7. Nomiyama, T., Haufroid, V., Buchet, J. P., Miyauchi, H., Tanaka, S., Yamauchi, H., Imamiya, S., Seki, Y., Omae, K., and Lison, D. (2001) Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N,N-dimethylformamide exposure in Japanese workers. Int Arch Occup Environ Health 74: 519-522.

  8. Review

  9. Nomiyama, T., Tsukahara, T., and Tsuda, Y. (2010) Exposure to Methyl iodine and sulfuryl fluoride used as fumigant and their health effects. Occup Health Review 22: 153-165. (in Japanese)

  10. Monograph

  11. Nomiyama, T., and Tsukahara, T. (2009) Cadmium poisoning. Practice of Internal Medicine: pp1553-1555. (in Japanese)

  12. Nomiyama, T., Tsukahara, T., and Tsuda, Y. (2009) Fumigation for cultural assets and occupational health. Health effects in fumigation workers: pp104-108. (in Japanese)